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3- (2- (3- (morpholinomethyl)phenyl)thieno(3,2- b)pyridin- 7- ylamino)phenol

inhibits discoidin domain receptor family tyrosine kinases; structure in first source

Also Known As:

LCB 03-0110

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aminopyridines: 77
    - 3-(2-(3-(morpholinomethyl)phenyl)thieno(3,2-b)pyridin-7-ylamino)phenol: 2
- Sulfur Compounds: 278
  - Thiophenes: 257
    - 3-(2-(3-(morpholinomethyl)phenyl)thieno(3,2-b)pyridin-7-ylamino)phenol: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Thiophenes: 257
    - 3-(2-(3-(morpholinomethyl)phenyl)thieno(3,2-b)pyridin-7-ylamino)phenol: 2
  - Pyridines: 88
    - Aminopyridines: 77
      - 3-(2-(3-(morpholinomethyl)phenyl)thieno(3,2-b)pyridin-7-ylamino)phenol: 2

Experts

1.	Jung, S H: 1 article (01/2013)
2.	Ryu, W-S: 1 article (01/2013)
3.	Sun, X: 1 article (01/2013)
4.	Yang, B-S: 1 article (01/2013)
5.	Cho, Jong Un: 1 article (03/2012)
6.	Jung, Seung Hee: 1 article (03/2012)
7.	Kim, Sun Young: 1 article (03/2012)
8.	Lee, Hyangsook: 1 article (03/2012)
9.	Park, Tae Kyo: 1 article (03/2012)
10.	Phan, Trong Nhat: 1 article (03/2012)

Related Diseases

1.	Allergic Contact Dermatitis 01/01/2013 - "Topical administration of the pan-Src kinase inhibitors, dasatinib and LCB 03-0110, prevents allergic contact dermatitis in mice."
2.	Hypertrophic Cicatrix (Hypertrophic Scar) 03/01/2012 - "LCB 03-0110 applied topically to full excisional wounds on rabbit ears suppressed the accumulation of myofibroblast and macrophage cells in the healing wound and reduced hypertrophic scar formation after wound closing, without delaying the wound closing process. "
3.	Wounds and Injuries (Trauma) 03/01/2012 - "LCB 03-0110 applied topically to full excisional wounds on rabbit ears suppressed the accumulation of myofibroblast and macrophage cells in the healing wound and reduced hypertrophic scar formation after wound closing, without delaying the wound closing process. "
4.	Cicatrix (Scar) 03/01/2012 - "LCB 03-0110, a novel pan-discoidin domain receptor/c-Src family tyrosine kinase inhibitor, suppresses scar formation by inhibiting fibroblast and macrophage activation."
5.	Atrophy 01/01/2013 - " Dasatinib and LCB 03-0110 could be used as effective agents for the treatment of ACD without the adverse side-effect of skin atrophy." 01/01/2013 - " To test the anti-ACD activity of dasatinib and LCB 03-0110 and compare it with that of tacrolimus (FK506) and triamcinolone acetonide (a glucocorticoid), which are widely used for topical treatment of ACD, and to examine the two compounds for their capacity to induce skin atrophy, a side-effect. "

Related Drugs and Biologics

1.	src-Family Kinases
2.	Tacrolimus (Prograf)
3.	Triamcinolone Acetonide (Azmacort)
4.	Glucocorticoids
5.	Discoidin Domain Receptors
6.	Dasatinib (BMS 354825)

Related Therapies and Procedures

1.	Topical Administration