sacran

01/01/2018 - "Recently, we demonstrated that sacran exerts anti-inflammatory activity by ameliorating the skin barrier function in patients with atopic dermatitis. "
01/01/2018 - "[Anti-inflammatory Effect of Sacran on Atopic Dermatitis]."
01/01/2014 - "Additionally, it was recently discovered that sacran has an anti-inflammatory effect for atopic dermatitis model mice. "
12/01/2017 - "In the present study, we tested the efficacy of sacran application in healthy individuals who reported previous symptoms of dry or inflamed skin, to evaluate the potential benefits of sacran for skin care in patients with mild atopic dermatitis. "
01/01/2018 - "In a previous study, we reported that sacran improves skin conditions in individuals who suffer from atopic dermatitis (AD), focusing on its trapping function against extrinsic stimuli compared with hyaluronic acid (HA). "

01/01/2018 - "These findings may be useful information for preparation of wound dressing materials using sacran, CyDs and drugs."
01/01/2018 - "Sac-HGF has potentially good properties for wound dressing application, due to not only the moisturizing effect but also the anti-inflammatory effect of sacran. "
01/01/2018 - "In this study, to develop and characterize sacran hydrogel films (Sac-HGFs) for wound dressing materials, we prepared a physically crosslinked-Sac-HGFs, and evaluated their physicochemical properties, cytotoxicity, skin hydration and wound healing ability. "
01/01/2018 - "[Potential Use of Sacran Hydrogels as Wound Dressing Material]."
05/01/2017 - "Recently, we revealed that sacran has the potential to form a hydrogel film (HGF) as a wound dressing material. "

01/01/2018 - "Furthermore, sacran solution significantly suppressed inflammation response in RAW264.7 cells. "
03/01/2021 - "The objective of this study was to investigate the effects of administering sacran, a sulfated polysaccharide, on liver biology, gut microbiota, oxidative stress, and inflammation on stroke-prone spontaneously hypertensive (SHRSP5/Dmcr) rats that develop fibrotic steatohepatitis with histological similarities to that of non-alcoholic steatohepatitis (NASH). "

03/01/2018 - "In the AD model mice, sacran markedly ameliorated AD symptoms such as scratching behavior and edema in ear. "
07/01/2016 - "Sacran markedly inhibited paw swelling and neutrophil infiltration in carrageenan-induced rat paw edema. "
07/01/2016 - "Also, sacran significantly suppressed kaolin-induced and dextran-induced rat paw edema throughout the duration of the study. "
07/01/2016 - "Furthermore, sacran significantly suppressed 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse ear edema and mRNA expression levels of cyclooxygenase (COX)-2 as well as pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6. "

01/01/2022 - "The Effects of Sacran, a Sulfated Polysaccharide, on Gut Microbiota Using Chronic Kidney Disease Model Rats."
01/01/2022 - "The aim of this study was to investigate the beneficial effects of sacran, a sulfated polysaccharide, on renal damage and intestinal microflora, in 5/6 nephrectomy rats as a model for chronic kidney disease (CKD). "