caudatin

01/01/2023 - "Moreover, CWHL and caudatin improved bone mineral density via decreasing levels of serum RANKL, tartrate-resistant acid phosphatase, and collagen type 1 cross-linked N-telopeptide and improving levels of serum alkaline phosphatase, osteoprotegerin, and osteocalcin compared with the OVX group without adverse effects such as dyslipidemia. "

01/01/2022 - "These data indicate that caudatin may be formulated as a potential therapeutic for osteosarcoma."
01/01/2022 - "Nevertheless, the role and mechanisms of caudatin in osteosarcoma (OS) remain unclear. "
01/01/2022 - "Caudatin Inhibits the Proliferation, Invasion, and Glycolysis of Osteosarcoma Cells via the Wnt/β- Catenin Pathway."

11/01/2012 - "In this study, we investigate the anti-cancer activity of caudatin in carcinomic human alveolar basal epithelial cell line A549 and anti-angiogenic activity in human umbilical vein endothelial cells (HUVECs). "
05/01/2022 - "Caudatin inhibited CRC cell malignancy through the hsa_circ_0060927/miR-421/miR-195-5p pathway, which provided a potential therapeutic agent for CRC."
05/01/2022 - "Furthermore, Caudatin treatment repressed tumor growth in vivo. "
05/01/2022 - "The impacts of Caudatin treatment on tumor growth in vivo were revealed by a xenograft tumor model assay. "
05/01/2022 - "Caudatin is extracted from radix cynanchi bungei and has an inhibitory effect on cancer progression. "

03/05/2015 - "Pharmacokinetics and tissue distribution studies of caudatin in conventional rats and hepatocellular carcinoma (HCC) model rats were then conducted for the first time. "
01/01/2012 - "Activation of ERK and JNK may be involved in caudatin-induced hepatoma cell apoptosis."
12/01/2013 - "In the present study, we investigated the antitumor activity of caudatin in the human hepatoma cell line SMMC‑7721 by analysis of cell viability, cell cycle distribution, apoptosis and metastasis. "
03/05/2015 - "Pharmacokinetics and tissue distribution study of caudatin in normal and diethylnitrosamine-induced hepatocellular carcinoma model rats."
03/05/2015 - "In our previous studies, caudatin showed selectivity on human hepatoma cell line SMMC7721 among several different tumor cell lines, and further in vivo tests validated the inhibitory action of caudatin against hepatic cancer using an H22 solid tumor model in mice, but to our knowledge, the biopharmaceutical properties of caudatin are largely unknown. "

12/01/2017 - "Based on the author's previous study, the antiangiogenic effect of caudatin against human glioma was explored, and the underlying mechanism was investigated. "
01/01/2016 - "In the present study, the growth suppressive effect and mechanism of caudatin on human glioma U251 and U87 cells were evaluated in vitro. "
10/01/2015 - "In the present study, the growth inhibitory effect and mechanism of caudatin on human glioma cells were evaluated in vitro. "
12/01/2017 - "The findings validated the antiangiogenic potential of caudatin in hunting human glioma."
12/01/2017 - "However, little information regarding the antiangiogenic properties of caudatin in human glioma is available. "