GEBR-7b

a PDE4D inhibitor; structure in first source

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

1.	Vomiting 11/29/2016 - "Pharmacological and behavioral studies on our hit GEBR-7b demonstrated that selective PDE4DIs could improve memory without causing emesis and sedation. " 12/01/2011 - "Our results demonstrate that GEBR-7b enhances memory functions at doses that do not cause emesis-like behaviour in rodents, thus offering a promising pharmacological perspective for the treatment of memory impairment." 12/01/2011 - "The effect of GEBR-7b on memory was 3 to 10 times more potent than that of rolipram, and its effective doses had no effect on surrogate measures of emesis in rodents. "
2.	Nausea 12/01/2011 - "The aim of the present study was to investigate the effect of the new drug, namely GEBR-7b, on memory performance, nausea, hippocampal cAMP and amyloid-β (Aβ) levels. "