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5,5',5',5'- (1,2,4,5- benzenetetrayl)tetrakis- (1- (3- phenylpyridinium)- 4- pentyne)

an alpha9alpha10 nicotinic acetylcholine receptor antagonist; structure in first source

Also Known As:

ZZ 204G; ZZ-204G; ZZ204G

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkynes: 217
      - 5,5',5',5'-(1,2,4,5-benzenetetrayl)tetrakis-(1-(3-phenylpyridinium)-4-pentyne): 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Pyridinium Compounds: 5
      - 5,5',5',5'-(1,2,4,5-benzenetetrayl)tetrakis-(1-(3-phenylpyridinium)-4-pentyne): 1

Experts

1.	Crooks, Peter A: 1 article (11/2011)
2.	Dowell, Cheryl: 1 article (11/2011)
3.	Dwoskin, Linda P: 1 article (11/2011)
4.	Holtman, Joseph R: 1 article (11/2011)
5.	McIntosh, J Michael: 1 article (11/2011)
6.	Wala, Elzbieta P: 1 article (11/2011)
7.	Zhang, Zhenfa: 1 article (11/2011)

Related Diseases

1.	Neuralgia (Stump Neuralgia) 11/30/2011 - "Parenteral administration of ZZ-204G dose-dependently decreased nociceptive behaviors (paw flinches) in the formalin test and mechanical hyperalgesia in the chronic constriction nerve injury model of neuropathic pain. " 11/30/2011 - "In summary, ZZ-204G represents a prototype small molecule antagonist for α9α10 nicotinic receptors and provides a novel molecular scaffold for analgesic agents with the potential to treat chronic inflammatory or neuropathic pain."
2.	Hyperalgesia 11/30/2011 - "Parenteral administration of ZZ-204G dose-dependently decreased nociceptive behaviors (paw flinches) in the formalin test and mechanical hyperalgesia in the chronic constriction nerve injury model of neuropathic pain. "

Related Drugs and Biologics

1.	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)
2.	Formaldehyde (Formol)
3.	Analgesics (Analgesic Drugs)