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vicanicin

has antineoplastic activity; isolated from Psoroma dimorphum; structure in first source

Networked: 2 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Amicosante, Gianfranco: 1 article (03/2013)
2.	Bozzi, Argante: 1 article (03/2013)
3.	Brisdelli, Fabrizia: 1 article (03/2013)
4.	Celenza, Giuseppe: 1 article (03/2013)
5.	Garbarino, Juan A: 1 article (03/2013)
6.	Nicoletti, Marcello: 1 article (03/2013)
7.	Perilli, Mariagrazia: 1 article (03/2013)
8.	Piovano, Marisa: 1 article (03/2013)
9.	Sellitri, Doriana: 1 article (03/2013)
10.	Caggia, S: 1 article (01/2012)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 01/05/2012 - "The combination of vicanicin (4) and protolichesterinic acid (5) with other anti-prostate cancer therapies could be considered a promising strategy that warrants further in vivo evaluation." 01/05/2012 - "Effect of vicanicin and protolichesterinic acid on human prostate cancer cells: role of Hsp70 protein." 01/05/2012 - "With the aim of identifying novel agents with antigrowth and pro-apoptotic activity on prostate cancer cells, in the present study, we evaluated the effect of five lichen secondary metabolites the depsides atranorin (1), diffrattaic (2) and divaricatic (3) acids, the depsidone vicanicin (4) and the protolichesterinic acid (5) on cell growth in androgen-sensitive (LNCaP) and androgen-insensitive (DU-145) human prostate cancer cells. "
2.	Neoplasms (Cancer) 03/01/2013 - "The purpose of this study was to investigate the effects of six lichen metabolites (diffractaic acid, lobaric acid, usnic acid, vicanicin, variolaric acid, protolichesterinic acid) on proliferation, viability and reactive oxygen species (ROS) level towards three human cancer cell lines, MCF-7 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and HCT-116 (colon carcinoma). "
3.	Carcinoma (Carcinomatosis) 03/01/2013 - "The purpose of this study was to investigate the effects of six lichen metabolites (diffractaic acid, lobaric acid, usnic acid, vicanicin, variolaric acid, protolichesterinic acid) on proliferation, viability and reactive oxygen species (ROS) level towards three human cancer cell lines, MCF-7 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and HCT-116 (colon carcinoma). "
4.	Adenocarcinoma 03/01/2013 - "The purpose of this study was to investigate the effects of six lichen metabolites (diffractaic acid, lobaric acid, usnic acid, vicanicin, variolaric acid, protolichesterinic acid) on proliferation, viability and reactive oxygen species (ROS) level towards three human cancer cell lines, MCF-7 (breast adenocarcinoma), HeLa (cervix adenocarcinoma) and HCT-116 (colon carcinoma). "

Related Drugs and Biologics

1.	Acids
2.	protolichesterinic acid
3.	Depsides
4.	Reactive Oxygen Species (Oxygen Radicals)
5.	Androgens
6.	lobaric acid
7.	diffractaic acid
8.	usnic acid
9.	atranorin
10.	depsidone

Related Therapies and Procedures

1.	Therapeutics