hexahydrocurcumin

from Zingiber officinale; structure in first source

Networked: 13 relevant articles (3 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Diarylheptanoids: 471
        Curcumin: 10678
        hexahydrocurcumin: 13
      - Benzene Derivatives: 17
        Phenols: 677
        Catechols: 121
        Curcumin: 10678
        hexahydrocurcumin: 13
  - Acyclic Hydrocarbons
    - Alkanes: 241
      - Heptanes: 70
        Diarylheptanoids: 471
        Curcumin: 10678
        hexahydrocurcumin: 13

Experts

1.	Suksamrarn, Apichart: 5 articles (01/2022 - 05/2012)
2.	Tocharus, Chainarong: 5 articles (01/2022 - 05/2012)
3.	Tocharus, Jiraporn: 5 articles (01/2022 - 05/2012)
4.	Chaichompoo, Waraluck: 2 articles (01/2022 - 06/2020)
5.	Qiu, Feng: 2 articles (09/2020 - 04/2015)
6.	Janyou, Adchara: 2 articles (06/2020 - 01/2017)
7.	Jittiwat, Jinatta: 2 articles (06/2020 - 01/2017)
8.	Wicha, Piyawadee: 2 articles (06/2020 - 01/2017)
9.	Chen, Chung-Yi: 2 articles (04/2018 - 11/2011)
10.	Srimuangwong, Khanitta: 2 articles (12/2012 - 05/2012)

Related Diseases

1.	Reperfusion Injury 06/01/2020 - "Hexahydrocurcumin (HHC), a major metabolite of curcumin, has been reported to have protective effects against ischemic and reperfusion damage. " 01/01/2017 - "Hexahydrocurcumin protects against cerebral ischemia/reperfusion injury, attenuates inflammation, and improves antioxidant defenses in a rat stroke model."
2.	Vascular Remodeling 01/01/2022 - "Hexahydrocurcumin ameliorates hypertensive and vascular remodeling in L-NAME-induced rats."
3.	Insulin Resistance 09/15/2020 - "Similar to CUR, hexahydrocurcumin (HHC) and octahydrocurcumin (OHC) improved insulin sensitivity by strengthening the PI3K-AKT-GSK3B signal and suppressing the phosphorylation of ERK/JNK in HG-induced insulin-resistant HepG2 cells. "
4.	Corneal Neovascularization 04/01/2018 - "Anti-angiogenic effect of hexahydrocurcumin in rat corneal neovascularization." 04/01/2018 - "This study was to investigate the anti-angiogenic effect of hexahydrocurcumin (HHC) to evaluate gene (p-basic fibroblast growth factor (bFGF)-SAINT-18 & p-vascular endothelial growth factor (VEGF)-SAINT-18 complex)-induced corneal neovascularization (CorNV) in rats. "
5.	Inflammation (Inflammations) 01/01/2017 - "The purpose of the present experiment was to investigate whether hexahydrocurcumin (HHC) attenuates brain damage and improves functional outcome via the activation of antioxidative activities, anti-inflammation, and anti-apoptosis following cerebral ischemia/reperfusion (I/R). " 01/01/2023 - "Hexahydrocurcumin mitigates angiotensin II-induced proliferation, migration, and inflammation in vascular smooth muscle cells." 01/01/2022 - "Hexahydrocurcumin (HHC), a major metabolite of curcumin, possesses several biological activities such as antioxidant, anti-inflammation, and cardioprotective properties. " 01/01/2017 - "Hexahydrocurcumin protects against cerebral ischemia/reperfusion injury, attenuates inflammation, and improves antioxidant defenses in a rat stroke model."

Related Drugs and Biologics

1.	Curcumin
2.	NG-Nitroarginine Methyl Ester (L-NAME)
3.	Insulin (Novolin)
4.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
5.	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)
6.	1-methyl-4-(9-dioleyl)methylpyridinium
7.	Antioxidants
8.	Fluorouracil (Carac)
9.	tetrahydrocurcumin
10.	Chitosan