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3- O- glucopyranosyl- 3,12,25- trihydroxydammar- 20(22)- ene

a ginsenoside Rh2 metabolite with antineoplastic activity; structure in first source

Also Known As:

3-O-beta-D-glucopyranosyl-3beta,12beta,25-trihydroxyl dammar-20(22)-ene; pseudo-G-Rh2

Networked: 3 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Terpenes: 1461
    - Triterpenes: 2493
      - Ginsenosides: 1010
        3-O-glucopyranosyl-3,12,25-trihydroxydammar-20(22)-ene: 3
Carbohydrates: 22023
- Glycosides: 2119
  - Saponins: 2867
    - Ginsenosides: 1010
      - 3-O-glucopyranosyl-3,12,25-trihydroxydammar-20(22)-ene: 3

Experts

1.	Xu, Huali: 3 articles (01/2021 - 12/2011)
2.	Yu, Xiaofeng: 3 articles (01/2021 - 12/2011)
3.	Sui, Dayun: 2 articles (01/2021 - 06/2018)
4.	Li, Yuangeng: 1 article (01/2021)
5.	Xia, Rui: 1 article (01/2021)
6.	Yu, Ping: 1 article (01/2021)
7.	Zhang, Fuyuan: 1 article (01/2021)
8.	Lu, Zeyuan: 1 article (06/2018)
9.	Lv, Chen: 1 article (06/2018)
10.	Tian, Yuan: 1 article (06/2018)

Related Diseases

1.	Stomach Neoplasms (Stomach Cancer) 12/01/2011 - "pseudo-G-Rh2 induces mitochondrial-mediated apoptosis in SGC-7901 human gastric cancer cells." 12/01/2011 - "This study was designed to investigate the effect of pseudo-G-Rh2, a novel metabolite of ginsenoside Rh2, on the apoptosis of SGC-7901 human gastric cancer cells. "
2.	Adenocarcinoma of Lung 06/01/2018 - "The aim of the present study was to evaluate the effect of pseudo-G-Rh2 on the apoptosis of lung adenocarcinoma A549 cells. "
3.	B-Cell Lymphoma (Lymphoma, B Cell) 06/01/2018 - "Furthermore, the results of western blotting revealed that B-cell lymphoma 2 (Bcl-2) expression was significantly decreased while Bcl-2-associated X protein expression was significantly upregulated in A549 cells with pseudo-G-Rh2 treatment. "
4.	Neoplasms (Cancer) 01/01/2021 - "However, whether this anti-cancer action of pseudo-G-Rh2 involves autophagy remains to be determined and explored. "

Related Drugs and Biologics

1.	ginsenoside Rh2
2.	bcl-2-Associated X Protein (bcl 2 Associated X Protein)