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1-(1- pentyl- 1H- indol- 3- yl)- 2- (2- methoxyphenyl)ethanone

a synthetic cannabinoid; structure in first source

Also Known As:

JWH 250; JWH-250; JWH250

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Borea, Pier Andrea: 1 article (06/2016)
2.	Canazza, Isabella: 1 article (06/2016)
3.	De Luca, Maria Antonietta: 1 article (06/2016)
4.	Marti, Matteo: 1 article (06/2016)
5.	Ossato, Andrea: 1 article (06/2016)
6.	Rimondo, Claudia: 1 article (06/2016)
7.	Serpelloni, Giovanni: 1 article (06/2016)
8.	Trapella, Claudio: 1 article (06/2016)
9.	Varani, Katia: 1 article (06/2016)
10.	Vincenzi, Fabrizio: 1 article (06/2016)

Related Diseases

1.	Cognitive Dysfunction 10/01/2013 - "Synthetic cannabinoid testing was performed by LC-MS-MS. Positive results included: JWH-018 (n = 4), 0.1-1.1 ng/mL; JWH-081 (n = 2) qualitative only; JWH-122 (n = 3), 2.5 ng/mL; JWH-210 (n = 4), 0.1 ng/mL; JWH-250 (n = 1), 0.38 ng/mL and AM-2201 (n = 6), 0.43-4.0 ng/mL. While there is good evidence of psychophysical impairment in these subjects, further structured data collection is needed to fully assess the relationship between synthetic cannabinoid use and psychomotor and cognitive impairment. "
2.	Seizures (Absence Seizure) 06/03/2016 - "In vivo studies showed that JWH-250 and JWH-073, administered separately, induced a marked hypothermia, increased pain threshold to both noxious mechanical and thermal stimuli, caused catalepsy, reduced motor activity, impaired sensorimotor responses (visual, acoustic and tactile), caused seizures, myoclonia, hyperreflexia and promote aggressiveness in mice. "
3.	Abnormal Reflex (Hyperreflexia) 06/03/2016 - "In vivo studies showed that JWH-250 and JWH-073, administered separately, induced a marked hypothermia, increased pain threshold to both noxious mechanical and thermal stimuli, caused catalepsy, reduced motor activity, impaired sensorimotor responses (visual, acoustic and tactile), caused seizures, myoclonia, hyperreflexia and promote aggressiveness in mice. "
4.	Hypothermia 06/03/2016 - "In vivo studies showed that JWH-250 and JWH-073, administered separately, induced a marked hypothermia, increased pain threshold to both noxious mechanical and thermal stimuli, caused catalepsy, reduced motor activity, impaired sensorimotor responses (visual, acoustic and tactile), caused seizures, myoclonia, hyperreflexia and promote aggressiveness in mice. "
5.	Catalepsy 06/03/2016 - "In vivo studies showed that JWH-250 and JWH-073, administered separately, induced a marked hypothermia, increased pain threshold to both noxious mechanical and thermal stimuli, caused catalepsy, reduced motor activity, impaired sensorimotor responses (visual, acoustic and tactile), caused seizures, myoclonia, hyperreflexia and promote aggressiveness in mice. "

Related Drugs and Biologics

1.	Cannabinoids
2.	(4- methyl- 1- naphthyl)- (1- pentylindol- 3- yl)methanone
3.	4- ethylnaphthalen- 1- yl- (1- pentylindol- 3- yl)methanone
4.	1-(5-fluoropentyl)-3-(1-naphthoyl)indole
5.	1-pentyl-3-(1-naphthoyl)indole
6.	(4- methoxy- 1- naphthalenyl)(1- pentyl- 1H- indol- 3- yl)methanone
7.	JWH-073