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L- arginyl- 2,5,7- tris(1,1- dimethylethyl)- L- tryptophyl- N- (2- phenylethyl)- L- argininamide

has antimicrobial activity

Also Known As:

LTX 109; LTX-109; LTX109; Lytixar

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - L-arginyl-2,5,7-tris(1,1-dimethylethyl)-L-tryptophyl-N-(2-phenylethyl)-L-argininamide: 4

Experts

1.	Husbyn, M: 1 article (11/2017)
2.	Johnson, L: 1 article (11/2017)
3.	Martin, H: 1 article (11/2017)
4.	Olsen, W M: 1 article (11/2017)
5.	Pawlak, J: 1 article (11/2017)
6.	Saravolatz, L D: 1 article (11/2017)
7.	Saravolatz, S: 1 article (11/2017)
8.	Wold, H: 1 article (11/2017)
9.	Scott, Richard W: 1 article (01/2017)
10.	Tew, Gregory N: 1 article (01/2017)

Related Diseases

1.	Infections 01/01/2015 - "Hence, LTX-109 has potential as a new and effective antimicrobial agent with a low propensity of resistance development that can prevent infections by MSSA/MRSA during hospitalization. " 08/25/2011 - "LTX 109 is a synthetic antimicrobial peptidomimetic (SAMP) currently in clinical phase II trials for topical treatment of infections of multiresistant bacterial strains. "
2.	Staphylococcal Infections 11/01/2017 - "The development of new synthetic antimicrobial peptides like LTX-109 provides a new class of drugs for the treatment of Staphylococcus aureus infections. "
3.	Impetigo (Impetigo Contagiosa) 01/01/2017 - "One lead compound, LTX-109, has entered clinical study as a topical agent to treat impetigo and nasal decolonization. "

Related Drugs and Biologics

1.	Peptidomimetics
2.	4-(4-sulfophenylazo)-2-mercuriphenol (SAMP)
3.	Anti-Infective Agents (Microbicides)
4.	Antimicrobial Peptides