gelomulide K

acts synergistically with paclitaxel against cancer; isolated from Gelonium multiflorum; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Neoplasms (Cancer) 08/01/2011 - "Additionally, in a xenograft model, gelomulide K induced PARP-1 activation and reduced tumor growth. "
2.	Breast Neoplasms (Breast Cancer) 08/01/2011 - "Here, we report that gelomulide K acts as a caspase-independent cell death-inducing agent that synergizes with paclitaxel in breast cancer cells and has low toxicity in normal cells. " 08/01/2011 - "Selective targeting of breast cancer cells through ROS-mediated mechanisms potentiates the lethality of paclitaxel by a novel diterpene, gelomulide K."