Posterior Amorphous Corneal Dystrophy

Also Known As:

Corneal Dystrophy, Posterior Amorphous

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Eye Diseases: 3522
- Corneal Diseases: 916
  - Hereditary Corneal Dystrophies: 820
    - Posterior Amorphous Corneal Dystrophy: 11
- Hereditary Eye Diseases: 18
  - Hereditary Corneal Dystrophies: 820
    - Posterior Amorphous Corneal Dystrophy: 11
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Hereditary Eye Diseases: 18
    - Hereditary Corneal Dystrophies: 820
      - Posterior Amorphous Corneal Dystrophy: 11

Related Diseases

1.	1 Posterior Polymorphous Corneal Dystrophy
2.	Brittle cornea syndrome 1

Experts

1.	Aldave, Anthony J: 4 articles (01/2021 - 08/2010)
2.	Frausto, Ricardo F: 3 articles (01/2021 - 01/2014)
3.	Rosenwasser, George O D: 2 articles (01/2014 - 08/2010)
4.	Basbus, Federico José: 1 article (04/2022)
5.	Chiaradía, Pablo Alberto: 1 article (04/2022)
6.	Cremona, Federico Andrés: 1 article (04/2022)
7.	Francipane, Liliana: 1 article (04/2022)
8.	Lucero Saá, Francisco: 1 article (04/2022)
9.	Menazzi, Sebastián: 1 article (04/2022)
10.	Barrington, Alice: 1 article (01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Posterior Amorphous Corneal Dystrophy:

1.	cytoplasmic protein A (PACD)IBA 10/01/2018 - "Posterior amorphous corneal dystrophy (PACD) (OMIM 612868) is a rare autosomal dominant disorder characterized by partial or complete posterior lamellar corneal opacification, decreased corneal thickness and flattening of the corneal curvature. " 12/01/2017 - "Posterior amorphous corneal dystrophy (PACD) is a rare disorder characterized by sheet-like opacification of the posterior corneal stroma, corneal thinning, and decreased corneal curvature. " 03/01/2017 - "We present a newborn diagnosed with posterior amorphous corneal dystrophy (PACD). " 01/01/2014 - "Posterior amorphous corneal dystrophy (PACD) is a rare, autosomal dominant disorder affecting the cornea and iris. " 08/01/2010 - "To identify the genetic basis of posterior amorphous corneal dystrophy (PACD) segregating in a large pedigree. "
2.	Small Leucine-Rich ProteoglycansIBA 04/01/2022 - "Posterior Amorphous Corneal Dystrophy: New Chromosomal Breakpoints in the Small Leucine-Rich Proteoglycan-Coding Region." 01/01/2018 - "Confirmation and refinement of the heterozygous deletion of the small leucine-rich proteoglycans associated with posterior amorphous corneal dystrophy." 01/01/2014 - "Posterior amorphous corneal dystrophy is associated with a deletion of small leucine-rich proteoglycans on chromosome 12." 01/01/2018 - "To present the clinical and cytogenetic features of a previously unreported family with posterior amorphous corneal dystrophy (PACD) associated with a heterozygous deletion of the small leucine-rich proteoglycan (SRLP) genes on chromosome 12. "

Therapies and Procedures

1.	Penetrating Keratoplasty 09/01/1990 - "Penetrating keratoplasty in the management of posterior amorphous corneal dystrophy." 01/01/1990 - "The youngest affected member of a family with a five-generation history of posterior amorphous corneal dystrophy underwent penetrating keratoplasty. "