Pseudoarylsulfatase A Deficiency

mutation in arylsulfatase A

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

1.	Metachromatic Leukodystrophy (Sulfatide Lipidosis) 05/01/1989 - "Genetically related to metachromatic leukodystrophy, pseudoarylsulfatase A deficiency has generally been felt to be a benign disorder. " 03/01/1983 - "Metachromatic leukodystrophy and pseudoarylsulfatase A deficiency in a Danish family." 04/01/1987 - "Cultured skin fibroblasts from normal individuals and healthy persons suffering from a pseudoarylsulfatase A deficiency (PD) degraded the P12-sulfatide, while in cells derived from a metachromatic leukodystrophy (MLD) patient it remained essentially intact. "
2.	Argininosuccinic Aciduria 01/01/1984 - "In this family, this test thus will be of no value in prenatal diagnosis to discriminate among low ASA fetuses with pseudoarylsulfatase A deficiency and fetuses with this unusual ASA deficiency variant."
3.	Multiple Sclerosis 01/01/1987 - "A 4-year old boy died of diffuse disseminated sclerosis (DDS) of the brain and was found to have also pseudoarylsulfatase A deficiency (PASAD) with about 20% residual arylsulfatase A (ASA) and cerebroside sulfatase (CS) activity. " 01/01/1987 - "Brain galactolipid content in a patient with pseudoarylsulfatase A deficiency and coincidental diffuse disseminated sclerosis, and in patients with metachromatic, adreno-, and other leukodystrophies."

1.	Galactolipids
2.	Cerebroside-Sulfatase (Arylsulfatase A)
3.	12- (1- pyrenedodecanoyl)sphingosylgalactosyl- O- 3- sulfate