Complementation Group A Molybdenum Cofactor Deficiency

Also Known As:

Molybdenum Cofactor Deficiency, Complementation Group A; Molybdenum Cofactor Deficiency Type A

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Inborn Errors Metabolism: 1162
    - Inborn Errors Metal Metabolism
      - Complementation Group A Molybdenum Cofactor Deficiency: 5
Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Inborn Errors Metabolism: 1162
    - Inborn Errors Metal Metabolism
      - Complementation Group A Molybdenum Cofactor Deficiency: 5
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Oxidoreductases: 13671
    - Nitrogenase: 83
      - Molybdoferredoxin: 1
        Complementation Group A Molybdenum Cofactor Deficiency: 5
- Coenzymes: 558
  - Molybdenum Cofactors
    - Molybdoferredoxin: 1
      - Complementation Group A Molybdenum Cofactor Deficiency: 5
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843

Related Diseases

1.	Brain Diseases (Brain Disorder)
2.	Pyridoxine-dependent epilepsy

Experts

1.	Adeniyi, Oluseyi: 1 article (01/2021)
2.	Donohue, Kathleen: 1 article (01/2021)
3.	Farrell, Sheila: 1 article (01/2021)
4.	Filie, Jane: 1 article (01/2021)
5.	Hager, Rebecca: 1 article (01/2021)
6.	Joffe, Hylton: 1 article (01/2021)
7.	Karp, Jacqueline: 1 article (01/2021)
8.	Kong, Nicolas: 1 article (01/2021)
9.	Li, Liang: 1 article (01/2021)
10.	Ma, Lian: 1 article (01/2021)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Complementation Group A Molybdenum Cofactor Deficiency:

1.	nulibryIBA 01/01/2021 - "Regulatory news: Nulibry (fosdenopterin) approved to reduce the risk of mortality in patients with molybdenum cofactor deficiency type A: FDA approval summary." 01/01/2018 - "Early diagnosis and treatment with cyclic pyranopterin monophosphate could arrest the progression of molybdenum cofactor deficiency type A. " 11/14/2015 - "Efficacy and safety of cyclic pyranopterin monophosphate substitution in severe molybdenum cofactor deficiency type A: a prospective cohort study." 05/17/2017 - "Novel outcomes are also being achieved in the treatment of some encephalopathies that are sensitive to vitamins or cofactors: triple therapy in pyridoxine dependency, treatment with thiamine for some subacute encephalopathies with involvement of the basal ganglia, treatment with folinic acid for children with cerebral folate deficiency, or treatment with cyclic pyranopterin monophosphate in molybdenum cofactor deficiency type A. "
2.	VitaminsIBA 05/17/2017 - "Novel outcomes are also being achieved in the treatment of some encephalopathies that are sensitive to vitamins or cofactors: triple therapy in pyridoxine dependency, treatment with thiamine for some subacute encephalopathies with involvement of the basal ganglia, treatment with folinic acid for children with cerebral folate deficiency, or treatment with cyclic pyranopterin monophosphate in molybdenum cofactor deficiency type A. "
3.	Thiamine (Aneurin)FDA Link 05/17/2017 - "Novel outcomes are also being achieved in the treatment of some encephalopathies that are sensitive to vitamins or cofactors: triple therapy in pyridoxine dependency, treatment with thiamine for some subacute encephalopathies with involvement of the basal ganglia, treatment with folinic acid for children with cerebral folate deficiency, or treatment with cyclic pyranopterin monophosphate in molybdenum cofactor deficiency type A. "
4.	Genetic Markers (Genetic Marker)IBA 01/01/2000 - "Prenatal diagnosis and carrier detection for molybdenum cofactor deficiency type A in northern Israel using polymorphic DNA markers."
5.	Folic Acid (Vitamin M)FDA LinkGeneric 05/17/2017 - "Novel outcomes are also being achieved in the treatment of some encephalopathies that are sensitive to vitamins or cofactors: triple therapy in pyridoxine dependency, treatment with thiamine for some subacute encephalopathies with involvement of the basal ganglia, treatment with folinic acid for children with cerebral folate deficiency, or treatment with cyclic pyranopterin monophosphate in molybdenum cofactor deficiency type A. "
6.	Leucovorin (Folinic Acid)FDA Link 05/17/2017 - "Novel outcomes are also being achieved in the treatment of some encephalopathies that are sensitive to vitamins or cofactors: triple therapy in pyridoxine dependency, treatment with thiamine for some subacute encephalopathies with involvement of the basal ganglia, treatment with folinic acid for children with cerebral folate deficiency, or treatment with cyclic pyranopterin monophosphate in molybdenum cofactor deficiency type A. "

Therapies and Procedures

Therapeutics

05/17/2017 - "Novel outcomes are also being achieved in the treatment of some encephalopathies that are sensitive to vitamins or cofactors: triple therapy in pyridoxine dependency, treatment with thiamine for some subacute encephalopathies with involvement of the basal ganglia, treatment with folinic acid for children with cerebral folate deficiency, or treatment with cyclic pyranopterin monophosphate in molybdenum cofactor deficiency type A. "