HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

Otosclerosis 2

Also Known As:

OTSC2

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Disease Context: Research Results

Otorhinolaryngologic Diseases: 203
- Ear Diseases: 261
  - Otosclerosis: 1435
    - Otosclerosis 2: 3

Related Diseases

1.	Otosclerosis
2.	Otosclerosis 3
3.	Otosclerosis 5

Experts

1.	Hamilton, B E: 1 article (06/2014)
2.	Nguyen, A: 1 article (06/2014)
3.	Nguyen-Huynh, A: 1 article (06/2014)
4.	Whetstone, J: 1 article (06/2014)
5.	Fransen, E: 1 article (04/2010)
6.	Govaerts, P J: 1 article (04/2010)
7.	Hellings, N: 1 article (04/2010)
8.	Hendrickx, J-J: 1 article (04/2010)
9.	Schatteman, I: 1 article (04/2010)
10.	Schrauwen, I: 1 article (04/2010)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Otosclerosis 2:

1.	T-Cell Antigen Receptors (T-Cell Receptor)IBA 04/01/2010 - "This study focused on the exploration of the second otosclerosis locus on chromosome 7q34-36 (OTSC2), holding the T-cell receptor beta locus (TRB locus). " 04/01/2010 - "Involvement of T-cell receptor-beta alterations in the development of otosclerosis linked to OTSC2." 04/01/2010 - "A significantly lower T-cell receptor-beta (TCR-beta) mRNA expression and percentage of blood circulating TCR-alphabeta(+) T cells was detected in OTSC2 patients compared with controls and patients with the complex form of the disease. "
2.	Messenger RNA (mRNA)IBA 04/01/2010 - "A significantly lower T-cell receptor-beta (TCR-beta) mRNA expression and percentage of blood circulating TCR-alphabeta(+) T cells was detected in OTSC2 patients compared with controls and patients with the complex form of the disease. "
3.	alpha2 Subunit Collagen Type IIBA 04/01/2006 - "Linkage analysis excluded linkage to the four known otosclerosis loci (OTSC1, OTSC2, OTSC3, and OTSC5), as well as to the COL1A1 and COL1A2 genes. "

Therapies and Procedures

1.	Prostheses and Implants (Prosthesis) 06/01/2014 - "Surgically confirmed abnormalities included 7 of 7 incus erosions, 3 of 6 piston re-sizings, 3 of 5 granulation tissues, 3 of 5 prosthesis disconnections, 3 of 4 obliterative otosclerosis, 2 of 2 oval window dislocations, and 1 labyrinthine ossificans. "