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Coppock-Like Cataract

Also Known As:

Cataract, Coppock-Like; Cataract, Embryonic Nuclear

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Eye Diseases: 3522
- Lens Diseases: 7
  - Cataract: 28071
    - Coppock-Like Cataract: 4

Related Diseases

1.	Cataract (Cataracts)

Experts

1.	Liang, Jack J-N: 2 articles (12/2008 - 09/2004)
2.	Hanson, Mark: 1 article (12/2008)
3.	Liu, Bing-Fen: 1 article (12/2008)
4.	Song, Shuhua: 1 article (12/2008)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Coppock-Like Cataract:

1.	gamma-CrystallinsIBA 02/01/1994 - "Reactivation of the psi gamma E gene and concomitant overexpression of the gamma-crystallin fragment could be the cause of the Coppock-like cataract." 02/01/1994 - "The locus for the hereditary human Coppock-like cataract (CCL) is closely linked to a particular combination of polymorphic TaqI sites within the human gamma-crystallin gene cluster. " 01/01/1987 - "The absolute correlation between the presence of haplotype P and cataract within this family shows that the gamma-crystallin gene cluster and the locus for the Coppock-like cataract are closely linked [logarithm of odds (lod) score of 7.58 at its maximum at phi = 0]. "
2.	Crystallins (Crystallin)IBA 12/01/2008 - "The human lens crystallin gene CRYGC T5P is associated with Coppock-like cataract and has a phenotype of a dust-like opacity of the fetal lens nucleus and deep cortical region. " 09/01/2004 - "Together with previous results obtained with a two-hybrid system assay of interactions between alphaA- and gammaC-crystallin, the present FRET and chaperone results indicate that loss of interactions of T5P mutant with other crystallins may play a larger role than the protection afforded by chaperone-like activity in Coppock-like cataract." 09/01/2004 - "T5P gammaC-crystallin mutation is associated with Coppock-like cataract, one of the autosomal dominant congenital cataracts. "
3.	crystallin gammaEIBA 02/01/1994 - "Activation of the gamma E-crystallin pseudogene in the human hereditary Coppock-like cataract."