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Inosine Triphosphatase Deficiency

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Disease Context: Research Results

Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Inborn Errors Metabolism: 1162
    - Inosine Triphosphatase Deficiency: 4
Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Inborn Errors Metabolism: 1162
    - Inosine Triphosphatase Deficiency: 4
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Acid Anhydride Hydrolases
      - Pyrophosphatases: 171
        Inosine Triphosphatase Deficiency: 4

Related Diseases

1.	Anemia
2.	Drug-Related Side Effects and Adverse Reactions
3.	Chronic Hepatitis C
4.	Infections

Experts

1.	Bordbar, Aarash: 1 article (10/2015)
2.	Jamshidi, Neema: 1 article (10/2015)
3.	McCloskey, Douglas: 1 article (10/2015)
4.	Palsson, Bernhard O: 1 article (10/2015)
5.	Sonnenschein, Nikolaus: 1 article (10/2015)
6.	Zielinski, Daniel C: 1 article (10/2015)
7.	Aghemo, A: 1 article (12/2013)
8.	Clark, P J: 1 article (12/2013)
9.	Colombo, M: 1 article (12/2013)
10.	D'Ambrosio, R: 1 article (12/2013)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Inosine Triphosphatase Deficiency:

1.	Ribavirin (Virazole)FDA LinkGeneric 10/28/2015 - "Finally, we use the models to identify individuals at risk for a drug side effect (ribavirin-induced anemia) and how genetic variation (inosine triphosphatase deficiency) may protect against this side effect. " 05/29/2011 - "Last year it was shown that two genetic variants leading to inosine triphosphatase deficiency protect against haemolytic anemia in patients receiving ribavirin during antiviral treatment for chronic HCV infection."
2.	DNA (Deoxyribonucleic Acid)IBA 01/01/2002 - "DNA polymorphisms in ITPA including basis of inosine triphosphatase deficiency."
3.	Antiviral Agents (Antivirals)IBA 05/29/2011 - "Last year it was shown that two genetic variants leading to inosine triphosphatase deficiency protect against haemolytic anemia in patients receiving ribavirin during antiviral treatment for chronic HCV infection."

Therapies and Procedures

1.	Therapeutics 12/01/2013 - "Inosine triphosphatase deficiency helps predict anaemia, anaemia management and response in chronic hepatitis C therapy."