Lattice Type IIIA Corneal Dystrophy

mutation in TGFBI

Also Known As:

Corneal Dystrophy, Lattice Type IIIA; Lattice Corneal Dystrophy, Type IIIA

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

1.	Amyloid Plaque
2.	gelatinous drop-like Corneal dystrophy

Drugs and Important Biological Agents (IBA) related to Lattice Type IIIA Corneal Dystrophy:

1.	Amyloid (Amyloid Fibrils)IBA 04/01/1999 - "To assess the relative distribution in the cornea of amyloid and (beta)ig-h3 gene product in lattice corneal dystrophy type IIIA (LCD-IIIA). " 04/01/1999 - "Amyloid and Pro501 Thr-mutated (beta)ig-h3 gene product colocalize in lattice corneal dystrophy type IIIA." 03/01/1991 - "Histopathologic examination revealed accumulations of varying sized amyloid deposits in the stroma and ribbons of amyloid between the stroma and Bowman's layer typical of lattice corneal dystrophy type III. We have named the disease in this family lattice corneal dystrophy type IIIA, because of three differences from lattice corneal dystrophy type III: the presence of corneal erosions, the occurrence in whites, and the autosomal dominant inheritance pattern."
2.	Transforming Growth Factors (Transforming Growth Factor)IBA 05/28/2022 - "Here, we report a novel de novo L509P mutation not located in a known hot spot of the transforming growth factor-β-induced (TGFBI) gene and its clinical phenotype, which resembles that of lattice corneal dystrophy type IIIA (LCD IIIA). "
3.	betaIG-H3 protein (keratoepithelin)IBA 03/01/1998 - "A kerato-epithelin (betaig-h3) mutation in lattice corneal dystrophy type IIIA."

1.	Slit Lamp 05/28/2022 - "De Novo L509P Mutation of the TGFBI Gene Associated with Slit-Lamp Findings of Lattice Corneal Dystrophy Type IIIA."