HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

Keratitis Fugax Hereditaria

Also Known As:

Keratoendotheliitis Fugax Hereditaria

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Disease Context: Research Results

Eye Diseases: 3522
- Corneal Diseases: 916
  - Keratitis: 6776
    - Keratitis Fugax Hereditaria: 4

Related Diseases

1.	Keratitis
2.	Cryopyrin-Associated Periodic Syndromes

Experts

1.	Järvinen, Reetta-Stiina: 2 articles (01/2020 - 01/2018)
2.	Kivelä, Tero T: 2 articles (01/2020 - 01/2018)
3.	Majander, Anna: 2 articles (01/2020 - 01/2018)
4.	Repo, Pauliina: 2 articles (01/2020 - 01/2018)
5.	Turunen, Joni A: 2 articles (01/2020 - 01/2018)
6.	Ala-Fossi, Olli: 1 article (01/2020)
7.	Immonen, Annamari T: 1 article (01/2020)
8.	Jaakkola, Aino M: 1 article (01/2020)
9.	Kawan, Sabita: 1 article (01/2020)
10.	Korsbäck, Anna: 1 article (01/2020)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Keratitis Fugax Hereditaria:

1.	NucleotidesIBA 10/11/2023 - "The aim of this study was to report a novel heterozygous variant c.1712G>T (p.Gly571Val) in the nucleotide-binding domain, leucine-rich repeat family, pyrin domain-containing 3 gene (NLRP3) in a previously unreported non-Finnish individual with keratitis fugax hereditaria (KFH). " 01/01/2018 - "Keratoendotheliitis Fugax Hereditaria: A Novel Cryopyrin-Associated Periodic Syndrome Caused by a Mutation in the Nucleotide-Binding Domain, Leucine-Rich Repeat Family, Pyrin Domain-Containing 3 (NLRP3) Gene."
2.	Leucine (L-Leucine)FDA Link 10/11/2023 - "The aim of this study was to report a novel heterozygous variant c.1712G>T (p.Gly571Val) in the nucleotide-binding domain, leucine-rich repeat family, pyrin domain-containing 3 gene (NLRP3) in a previously unreported non-Finnish individual with keratitis fugax hereditaria (KFH). " 01/01/2018 - "Keratoendotheliitis Fugax Hereditaria: A Novel Cryopyrin-Associated Periodic Syndrome Caused by a Mutation in the Nucleotide-Binding Domain, Leucine-Rich Repeat Family, Pyrin Domain-Containing 3 (NLRP3) Gene."
3.	InflammasomesIBA 11/16/2022 - "Functional consequences of pathogenic variant c.61G>C in the inflammasome gene NLRP3 underlying keratitis fugax hereditaria."
4.	Prednisolone (Predate)FDA LinkGeneric 11/16/2022 - "To elucidate the effect of NLRP3 variant c.61G>C on interleukin-1β (IL-1β) secretion in keratitis fugax hereditaria (KFH), a cryopyrin-associated periodic syndrome limited to the eye, and to probe the potential modifying role of prednisolone. "

Therapies and Procedures

1.

Penetrating Keratoplasty

01/01/2020 - "To apply in vivo corneal confocal microscopy (IVCM) to study the pathogenesis of keratitis (keratoendotheliitis) fugax hereditaria, an autosomal dominant cryopyrin-associated periodic keratitis, associated with the c.61G>C pathogenic variant in the NLRP3 gene, in its acute and chronic phase, and to report histopathologic findings after penetrating keratoplasty. "