Familial Cirrhosis with Pulmonary Hypertension

11/01/1977 - "Therapeutic efficacy of zinc in Indian childhood cirrhosis. "
01/01/1989 - "Zinc levels in serum and hair were estimated in 32 cases of Indian Childhood Cirrhosis (ICC)--14 in Stage II and 18 in Stage III. Levels were compared with 20 cases of age matched healthy controls. "
01/01/1989 - "Serum and hair zinc in Indian childhood cirrhosis."
02/01/1980 - "Hepatic zinc levels in Indian childhood cirrhosis."
10/01/1978 - "Hair--zinc in cases of Indian childhood cirrhosis."

12/01/1982 - "Renal clearance of amino acids in Indian childhood cirrhosis."
05/01/1981 - "The erythrocyte enzymes of glutamic acid metabolism (glutaminase I, glutaminase II, glutamic acid decarboxylase, glutamine synthetase, and transaminases) and related amino acids (glutamine, glutamic acid, aspartic acid, alanine, and gamma-aminobutyric acid) were estimated in 69 children with protein-energy malnutrition, 13 with nephrosis, and 10 with Indian childhood cirrhosis. "

01/01/1983 - "A study of serum and hepatic copper in Indian childhood cirrhosis."
06/09/1979 - "Morphological, histochemical, and chemical study of three necropsy specimens of liver in the terminal stage of Indian Childhood Cirrhosis revealed a strikingly high copper content. "
11/27/2021 - "Indian childhood cirrhosis is related to excessive copper ingestion, rarely seen in present era. "
07/28/1999 - "However, copper in excess is highly toxic and elevated copper concentrations in cells have been associated with several diseases, including non-Indian childhood cirrhosis (NICC) in man and copper toxicosis in Bedlington terriers. "
05/01/1999 - "Laboratory, histopathological findings and a proven chronic copper intoxication lead to the diagnosis of Indian childhood cirrhosis in a German girl. "

11/01/1987 - "Clinical trials of penicillamine in Indian childhood cirrhosis."
01/01/1996 - "Indian childhood cirrhosis (ICC) is an almost uniformly fatal disease whose outcome may be modified with penicillamine if given at a sufficiently early stage. "
01/01/1996 - "Long term survival in Indian childhood cirrhosis treated with D-penicillamine."
07/01/1991 - "This report is the first documentation of the histologic sequence of changes in Indian childhood cirrhosis on d-penicillamine treatment."
07/01/1991 - "Eight children who satisfied all the diagnostic criteria of classic Indian childhood cirrhosis were treated with d-penicillamine. "

12/01/1982 - "Orcein positive, non-HBs material in hepatocytes in Indian childhood cirrhosis."
06/09/1979 - "5 in whom a clinical and histological diagnosis of Indian Childhood Cirrhosis was made had massive orcein-staining deposits in liver cells. "
09/30/1978 - "Indian childhood cirrhosis presenting in Britain with orcein-positive deposits in liver and kidney."
06/24/1978 - "Orcein-positive liver deposits in Indian childhood cirrhosis."
07/19/1975 - "The surface and core componenets of hepatitis-B virus have not been detected in livers of patients suffering from Indian childhood cirrhosis using procedures such as immunoperoxidase, immunofluorescence, and orcein staining as well as electronmicroscopy. "

08/01/1989 - "To mimic the infant feeding practice associated with Indian childhood cirrhosis (ICC), bovine milk was stored for 6 h in indigenous brass vessels. "
07/01/1986 - "Elimination of brass utensils prevents Indian childhood cirrhosis."
01/01/1992 - "Previous studies have led to the hypothesis that the gross hepatic copper storage characteristic of Indian childhood cirrhosis (ICC) is due to the early introduction of animal milk feeds which have been contaminated with copper from brass household utensils. "
08/01/1989 - "Uptake of copper from brass vessels by bovine milk and its relevance to Indian childhood cirrhosis."
10/29/1983 - "Brass and copper household utensils are a possible source of the gross hepatic copper accumulation characteristic of Indian childhood cirrhosis (ICC). "

07/01/1983 - "Alkaline phosphatase (ALP) isoenzyme composition was studied in sera and liver from patients with Indian childhood cirrhosis (ICC). "
07/01/1983 - "Detection of Regan variant type of alkaline phosphatase isoenzyme in liver tissue of Indian childhood cirrhosis."
11/01/1980 - "Abnormal lactic dehydrogenase isoenzymes in patients of Indian childhood cirrhosis and their siblings."
11/01/1987 - "Enzymatic studies and isoenzyme pattern of gammaglutamyl transpeptidase (GGTP) in Indian childhood cirrhosis (CC)."

07/01/1980 - "Study of the role of tryptophan metabolism in Indian Childhood Cirrhosis."
08/19/1978 - "Indian childhood cirrhosis: an inherited disorder of tryptophan metabolism?"

11/01/1994 - "To investigate the possible synergy between copper and retrorsine (a pyrrolizidine alkaloid) as a cause of Indian Childhood Cirrhosis, four groups of male Wistar rats were fed the following diets from weaning: A. "
11/01/1996 - "To explore the hypothesis that a second xenobiotic agent is required with excess copper to produce Indian Childhood Cirrhosis, this study investigated the effect of the pyrrolizidine alkaloid retrorsine fed to the mother during the suckling period upon the serial changes in neonatal copper status. "

09/01/1974 - "Study of serum iron levels in Indian childhood cirrhosis."
01/01/1975 - "Liver-iron in Indian childhood cirrhosis."

12/01/1983 - "A clinico-pathological study of Indian childhood cirrhosis before and after steroid therapy."
01/01/1995 - "Reversal of Indian childhood cirrhosis by D-penicillamine therapy."
07/01/1987 - "D-penicillamine in the therapy of Indian childhood cirrhosis."
07/01/1983 - "Oral zinc therapy in Indian childhood cirrhosis."
11/01/1980 - "Zinc therapy in Indian childhood cirrhosis."

10/01/1994 - "These conditions include (mean prevalence of Mallory bodies in parentheses): Indian childhood cirrhosis (73%), alcoholic hepatitis (65%), alcoholic cirrhosis (51%), Wilson's disease (25%), primary biliary cirrhosis (24%), nonalcoholic cirrhosis (24%), hepatocellular carcinoma (23%), morbid obesity (8%) and intestinal bypass surgery (6%). "
12/01/1982 - "Tissues from patients with primary biliary cirrhosis, jejunoileal bypass, hepatocellular carcinoma, Wilson's disease, and Indian childhood cirrhosis were all positive for hyalin by hematoxylin and eosin staining. "

11/01/1999 - "Indian childhood cirrhosis-like disease in a Japanese boy undergoing liver transplantation."

07/01/1983 - "Environmental factors: Extensive use of copper utensils and vegetarian diet in the causation of Indian childhood cirrhosis."