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HLA-B58

Networked: 7 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Cho, Sang-Heon: 2 articles (01/2014 - 11/2011)
2.	Jung, Jae-Woo: 2 articles (01/2014 - 11/2011)
3.	Kang, Hye-Ryun: 2 articles (01/2014 - 11/2011)
4.	Kim, Ju-Young: 1 article (01/2014)
5.	Park, Seon-Yang: 1 article (01/2014)
6.	Yoon, Sung-Soo: 1 article (01/2014)
7.	Chang, Yoon-Seok: 1 article (11/2011)
8.	Joo, Kwon Wook: 1 article (11/2011)
9.	Kim, Sae-Hoon: 1 article (11/2011)
10.	Kim, Yon-Su: 1 article (11/2011)

Related Diseases

1.	Hypersensitivity (Allergy) 11/01/2011 - "Screening tests for HLA-B58 in CRI patients will be clinically helpful in preventing severe allopurinol hypersensitivity reactions." 11/01/2011 - "This study was conducted to find out the incidence of allopurinol-induced hypersensitivity on patients with chronic renal insufficiency (CRI) according to HLA-B58 and the clinical implications of HLA-B58 as a risk marker for the development of allopurinol-induced hypersensitivity. " 01/01/2014 - "In conclusion, HLA-DR9 and DR14, but not HLA-B58, are associated with hypersensitivity reaction by allopurinol when administered in patients with hematologic malignancy prior to chemotherapy. "
2.	Chronic Renal Insufficiency 11/01/2011 - "HLA-B58 can help the clinical decision on starting allopurinol in patients with chronic renal insufficiency." 11/01/2011 - "This study was conducted to find out the incidence of allopurinol-induced hypersensitivity on patients with chronic renal insufficiency (CRI) according to HLA-B58 and the clinical implications of HLA-B58 as a risk marker for the development of allopurinol-induced hypersensitivity. "
3.	Cicatrix (Scar) 11/01/2011 - "In this study, the incidence of allopurinol-induced SCARs was considerably high in CRI patients with HLA-B58. " 11/01/2011 - "This finding indicates that the presence of HLA-B58 may increase the risk of allopurinol-induced SCARs. " 11/01/2011 - "The incidence of allopurinol-induced SCARs in CRI shows a wide disparity according to HLA-B58 [18% in HLA-B58 (+) versus 0% in HLA-B58 (-)]. " 11/01/2011 - "The HLA-B58 allele was present in all patients with allopurinol-induced SCARs, while the frequency of HLA-B58 was only 9.5% in allopurinol-tolerant patients (P < 0.05). "
4.	Genetic Predisposition to Disease (Genetic Predisposition) 06/01/2008 - "HLA-B58 allele can be associated with the genetic susceptibility for patients with acute lymphocytic leukaemia. " 06/01/2008 - "HLA-B58, DR12, DR14 alleles appear to contribute to the genetic susceptibility of patients with chronic myelocytic leukemia. "
5.	Hematologic Neoplasms (Hematological Malignancy) 01/01/2014 - "In conclusion, HLA-DR9 and DR14, but not HLA-B58, are associated with hypersensitivity reaction by allopurinol when administered in patients with hematologic malignancy prior to chemotherapy. "

Related Drugs and Biologics

1.	Allopurinol (Remid)
2.	HLA-B57 antigen
3.	HLA-A24 Antigen
4.	HLA-DRB1 Chains (HLA DRB1)
5.	HLA-B Antigens (HLA-B)
6.	Epitopes
7.	HLA-DR9 antigen

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)