saucerneol D

has antioxidant, anti-infllammatory, and antiasthmatic activities; a sesquilignan isolated from Saururus chinensis; structure in first source

Networked: 2 relevant articles (1 outcomes, 2 trials/studies)

1.	Pneumonia (Pneumonitis) 06/01/2011 - "Histopathology studies revealed a marked decrease in lung inflammation and goblet cell hyperplasia after saucerneol D treatment. "
2.	Hyperplasia 06/01/2011 - "Histopathology studies revealed a marked decrease in lung inflammation and goblet cell hyperplasia after saucerneol D treatment. "
3.	Hyperpigmentation 08/01/2011 - "Taken together, this study provides saucerneol D down-regulated the gene expression of tyrosinase, resulting in the inhibition of cAMP-induced melanin biosynthesis, and suggests pharmacological potential of the lignan structure in skin hyperpigmentation."
4.	Experimental Melanoma 08/01/2011 - "In the present study, saucerneol D as a lignan constituent of Saururus chinensis (Saururaceae family) efficiently inhibited melanin production with IC(50) values of 188-297 nM in B16 melanoma cells stimulated with α-melanocyte stimulating hormone (α-MSH) or other cAMP elevators. "
5.	Inflammation (Inflammations) 06/01/2011 - "In our experiments, saucerneol D treatment reduced airway inflammation and suppressed oxidative stress in an OVA-induced asthma model." 06/01/2011 - "We evaluated the ability of saucerneol D, a tetrahydrofuran-type sesquilignan isolated from Saururus chinensis, to regulate airway inflammation in an ovalbumin (OVA)-induced airway inflammation model. " 06/01/2011 - "Antioxidant and antiasthmatic effects of saucerneol D in a mouse model of airway inflammation."

1.	Lignans
2.	Monophenol Monooxygenase (Tyrosinase)
3.	Melanocyte-Stimulating Hormones (MSH)
4.	Melanins (Melanin)
5.	Anti-Asthmatic Agents (Antiasthmatic Drugs)
6.	Ovalbumin
7.	Antioxidants
8.	tetrahydrofuran