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N- (2- chloroacetyl)- 6- (2- oxo- 4- phenylimidazolidin- 1- ylsulfonyl)- 3,4- dihydroquinoline- 1(2H)- carboxamide

antineoplastic; structure in first source

Also Known As:

CSOPSDC cpd

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Imidazoles: 150
      - Imidazolidines: 39
        N-(2-chloroacetyl)-6-(2-oxo-4-phenylimidazolidin-1-ylsulfonyl)-3,4-dihydroquinoline-1(2H)-carboxamide: 1

Experts

1.	Jung, Sang-Hun: 1 article (08/2011)
2.	Kang, Jong Seong: 1 article (08/2011)
3.	Kim, Hwan-Mook: 1 article (08/2011)
4.	Kim, Nam-Soo: 1 article (08/2011)
5.	Lee, Ki-Cheul: 1 article (08/2011)
6.	Sharma, Vinay K: 1 article (08/2011)
7.	Subramanian, Santhosh: 1 article (08/2011)
8.	Thanigaimalai, Pillaiyar: 1 article (08/2011)

Related Diseases

1.

Neoplasms (Cancer)

08/01/2011 - "Among them, N-(2-chloroacetyl)-6-(2-oxo-4-phenylimidazolidin-1-ylsulfonyl)-3,4-dihydroquinoline-1(2H)-carboxamide (4m) and N-cyclohexyl-6-(2-oxo-4-phenylimidazolidin-1-ylsulfonyl)-3,4-dihydroquinoline-1(2H)-carboxamide (4n) exhibited comparable in vitro anticancer activity to doxorubicin against A549, KATO III and K562 cell lines and gave superior xenographic results against NCI-H23 and SW620 cancer cell lines. "

Related Drugs and Biologics

1.	Doxorubicin (Adriamycin)
2.	N- cyclohexyl- 6- (2- oxo- 4- phenylimidazolidin- 1- ylsulfonyl)- 3,4- dihydroquinoline- 1(2H)- carboxamide