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O2',O3',O5'- triacetyl- N6- (3- hydroxylaniline)adenosine

an AMPK activator; structure in first source

Also Known As:

WS 070117; WS-070117; WS070117

Networked: 4 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Adenosine: 12431
        O2',O3',O5'-triacetyl-N6-(3-hydroxylaniline)adenosine: 4
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Adenosine: 12431
      - O2',O3',O5'-triacetyl-N6-(3-hydroxylaniline)adenosine: 4
  - Ribonucleosides: 49
    - Adenosine: 12431
      - O2',O3',O5'-triacetyl-N6-(3-hydroxylaniline)adenosine: 4

Experts

1.	Zhu, Haibo: 3 articles (06/2016 - 04/2011)
2.	Li, Yan: 2 articles (06/2016 - 04/2011)
3.	Lian, Zeqin: 2 articles (01/2012 - 04/2011)
4.	Hu, Jinping: 1 article (06/2016)
5.	Jia, Yufei: 1 article (06/2016)
6.	Li, Sheng: 1 article (06/2016)
7.	Wang, Baolian: 1 article (06/2016)
8.	Wang, Dongmei: 1 article (06/2016)
9.	Wu, Xiangmeng: 1 article (06/2016)
10.	Jiang, Chun-Ying: 1 article (05/2014)

Related Diseases

1.	Hyperlipidemias (Hyperlipidemia) 05/01/2014 - "In this study, 1H NMR-based metabolomics was used to investigate the dose-related effects of WS070117 on hyperlipidemia of high-fat-fed hamsters. " 06/01/2016 - "2',3',5'-Tri-O-acetyl-N6-(3-hydroxylaniline)adenosine (IMM-H007, once called WS070117) is being developed as a novel anti-hyperlipidemia agent for its high efficacy and low toxicity. " 01/01/2012 - "This work demonstrates the promise of applying (1)H NMR metabonomics to evaluate the beneficial effects of WS070117 which may be a good drug candidate for hyperlipidemia." 04/29/2011 - "These new findings identify WS070117 as a novel molecule that regulates lipid metabolism in the hyperlipidemia hamster model. " 04/29/2011 - "WS070117 is a novel small molecule compound that significantly improves lipid metabolism disorders in high-fat-diet (HFD) induced hyperlipidemia in hamsters. "
2.	Lipid Metabolism Disorders (Metabolism Disorders, Lipid) 04/29/2011 - "WS070117 is a novel small molecule compound that significantly improves lipid metabolism disorders in high-fat-diet (HFD) induced hyperlipidemia in hamsters. "
3.	Body Weight (Weight, Body) 04/29/2011 - "We evaluated liver/body weight ratio, liver histology, serum and hepatic lipid content in HFD-fed hamsters treated with WS070117 for 8 weeks. "

Related Drugs and Biologics

1.	Lipids