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OP-1118

antibacterial major metabolite of fidaxomicin

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Glycosides: 2119
  - Aminoglycosides: 5131
    - OP-1118: 2

Experts

1.	Chen, Xinhua: 1 article (01/2018)
2.	Kelly, Ciaran P: 1 article (01/2018)
3.	Koon, Hon Wai: 1 article (01/2018)
4.	Lee, Elaine C: 1 article (01/2018)
5.	Mussatto, Caroline C: 1 article (01/2018)
6.	Ortiz, Christina: 1 article (01/2018)
7.	Pothoulakis, Charalabos: 1 article (01/2018)
8.	Tran, Diana Hoang-Ngoc: 1 article (01/2018)
9.	Wang, Jiani: 1 article (01/2018)
10.	Babakhani, Farah: 1 article (09/2011)

Related Diseases

1.	Inflammation (Inflammations) 01/01/2018 - "We showed that fidaxomicin and its primary metabolite OP-1118 significantly inhibited toxin A-mediated intestinal inflammation in mice in vivo and toxin A-induced cell rounding in vitro We aim to determine whether fidaxomicin and OP-1118 possess anti-inflammatory effects against toxin A and toxin B in the human colon and examine the mechanism of this response. "
2.	Clostridium Infections 09/01/2011 - "Fidaxomicin (FDX), a narrow-spectrum antibiotic recently shown to be superior to vancomycin in providing sustained clinical response to Clostridium difficile infection, was investigated along with its major metabolite, OP-1118, with regard to their postantibiotic effects (PAE). "

Related Drugs and Biologics

1.	Fidaxomicin
2.	Vancomycin
3.	Anti-Bacterial Agents (Antibiotics)