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6- fluoro- 2- (3- fluorophenyl)- 4- (cyanoanilino)quinazoline

antineoplastic; structure in first source

Also Known As:

HMJ-30

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - 6-fluoro-2-(3-fluorophenyl)-4-(cyanoanilino)quinazoline: 2

Experts

1.	Chiu, Yu-Jen: 2 articles (08/2014 - 09/2011)
2.	Hour, Mann-Jen: 2 articles (08/2014 - 09/2011)
3.	Jin, Yi-An: 2 articles (08/2014 - 09/2011)
4.	Kuo, Sheng-Chu: 2 articles (08/2014 - 09/2011)
5.	Lu, Chi-Cheng: 2 articles (08/2014 - 09/2011)
6.	Yang, Jai-Sing: 2 articles (08/2014 - 09/2011)
7.	Chen, Hao-Ping: 1 article (08/2014)
8.	Chiang, Jo-Hua: 1 article (08/2014)
9.	Wu, Tian-Shung: 1 article (08/2014)
10.	Chen, Hui-Jye: 1 article (09/2011)

Related Diseases

1.	Osteosarcoma (Osteogenic Sarcoma) 09/01/2011 - "In this study, we developed a novel quinazoline HMJ-30 to investigate the cell growth inhibition and apoptotic responses in U-2 OS human osteogenic sarcoma cells. " 09/01/2011 - "Novel quinazoline HMJ-30 induces U-2 OS human osteogenic sarcoma cell apoptosis through induction of oxidative stress and up-regulation of ATM/p53 signaling pathway."
2.	Neoplasms (Cancer) 08/01/2014 - "In summary, HMJ-30 may provide a potential therapeutic effect for the anti-vascular targeting of angiogenesis during cancer treatment."
3.	Ataxia Telangiectasia (Louis Bar Syndrome) 09/01/2011 - "HMJ-30 induced early phosphorylation of p53(Ser18) was through the activation of ataxia telangiectasia mutated (ATM) in U-2 OS cells. "

Related Drugs and Biologics

1.	Quinazolines
2.	Therapeutic Uses