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XL 888
structure in first source
Also Known As:
XL-888; XL888 cpd
Networked:
1
relevant articles (
0
outcomes,
1
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Carboxylic Acids: 973
Carbocyclic Acids
Phthalic Acids: 1
XL 888: 1
Aza Compounds: 3
Azabicyclo Compounds
XL 888: 1
Heterocyclic Compounds: 198
Bridged-Ring Heterocyclic Compounds
Heterocyclic Bridged Bicyclo Compounds
Azabicyclo Compounds
XL 888: 1
Related Diseases
1.
Liver Neoplasms (Liver Cancer)
10/04/2023 - "
The results revealed that the combination of DOX and XL-888 potently induced apoptosis in liver cancer cell lines rather than using drugs alone.
"
10/04/2023 - "
The single and combined cytotoxic effects of DOX and XL-888 on liver cancer cell lines HepG2 and HUH-7 were determined by MTT assay.
"
10/04/2023 - "
The combined treatment of DOX and XL-888 demonstrated synergistic cytotoxic and apoptotic effects on liver cancer cell lines, presenting a promising approach for combination therapy in liver cancer.
"
10/04/2023 - "
Therefore, the aim of the study to investigate its cytotoxic and apoptotic effects on liver cancer cell lines by combining the classical chemotherapeutic drug doxorubicin (DOX) and a targeted agent, the new generation HSP90 inhibitor XL-888.
"
10/04/2023 - "
Synergistic induction of apoptosis in liver cancer cells: exploring the combined potential of doxorubicin and XL-888.
"
Related Drugs and Biologics
1.
Doxorubicin (Adriamycin)
Related Therapies and Procedures
1.
Therapeutics