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1-O-hexadecylglycerophosphocholine

Also Known As:

1-O-hexadecyl-sn-glycerophosphocholine; C16:0 lyso-PAF

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
Lipids: 114793
- Membrane Lipids: 1591
  - Phospholipids: 11903
    - Glycerophosphates: 118
      - Phosphatidic Acids: 358
        Glycerophospholipids: 689
        Phospholipid Ethers: 36
        Platelet Activating Factor: 2984
        1-O-hexadecylglycerophosphocholine: 2
Biological Factors: 2472
- Blood Coagulation Factors: 5376
  - Platelet Activating Factor: 2984
    - 1-O-hexadecylglycerophosphocholine: 2
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Platelet Activating Factor: 2984
      - 1-O-hexadecylglycerophosphocholine: 2

Experts

1.	Bennett, Steffany A L: 1 article (12/2009)
2.	Blanchard, Alexandre P: 1 article (12/2009)
3.	Bourgeois, André J G: 1 article (12/2009)
4.	Ethier, Martin: 1 article (12/2009)
5.	Figeys, Daniel: 1 article (12/2009)
6.	Fraser, Paul E: 1 article (12/2009)
7.	Hou, Weimin: 1 article (12/2009)
8.	Moffat, Tia C: 1 article (12/2009)
9.	Park, David S: 1 article (12/2009)
10.	Rashidian, Juliet: 1 article (12/2009)

Related Diseases

1.	Inflammation (Inflammations) 03/01/1996 - "Incubation of mucosa from areas of active inflammation in ulcerative colitis with the calcium ionophore A23187 increased the levels of C16:0 PAF by 2-3 fold and also increased the levels of C16:0 lyso-PAF. "
2.	Ulcerative Colitis 03/01/1996 - "Both C16:0 lyso-PAF and C18:0 lyso-PAF were found in mucosa from normal and ulcerative colitis surgical resections and in endoscopic biopsies from ulcerative colitis and normal tissue. " 03/01/1996 - "Incubation of mucosa from areas of active inflammation in ulcerative colitis with the calcium ionophore A23187 increased the levels of C16:0 PAF by 2-3 fold and also increased the levels of C16:0 lyso-PAF. "
3.	Alzheimer Disease (Alzheimer's Disease) 12/08/2009 - "Acute intraneuronal accumulation of C16:0 PAF but not C16:0 lyso-PAF initiated cyclin-dependent kinase 5-mediated hyperphosphorylation of tau on Alzheimer disease-specific epitopes. " 12/08/2009 - "We found that specific isoforms defined by a palmitic acid (16:0) at the sn-1 position, namely 1-O-hexadecyl-2-acetyl-sn-glycero-3-phosphocholine (C16:0 PAF) and 1-O-hexadecyl-sn-glycero-3-phosphocholine (C16:0 lyso-PAF), were elevated in the temporal cortex of Alzheimer disease patients, transgenic mice expressing human familial disease-mutant amyloid precursor protein, and human neurons directly exposed to amyloid-beta(42) oligomers. "

Related Drugs and Biologics

1.	1- hexadecyl- 2- acetyl- glycero- 3- phosphocholine (APRL)
2.	Calcium Ionophores
3.	Protein Isoforms (Isoforms)
4.	Palmitic Acid (Hexadecanoic Acid)
5.	Cyclin-Dependent Kinases (cdk Proteins)
6.	Proteins (Proteins, Gene)
7.	Epitopes
8.	Amyloid (Amyloid Fibrils)
9.	Calcimycin (A23187)
10.	O-deacetyl platelet activating factor