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N- (4- (3- (1- ethyl- 3- fluoropiperidine- 4- ylamino)- 1H- pyrazolo(3,4- b)pyridin- 4- yloxy)- 3- fluorophenyl)- 2- (4- fluorophenyl)- 3- oxo- 2,3- dihydropyridazine- 4- carboxamide

a MET kinase inhibitor; structure in first source

Also Known As:

AR 00451896; AR-00451896; AR00451896; GNE-A compound

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - N-(4-(3-(1-ethyl-3-fluoropiperidine-4-ylamino)-1H-pyrazolo(3,4-b)pyridin-4-yloxy)-3-fluorophenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide: 1
  - Pyridazines: 11
    - N-(4-(3-(1-ethyl-3-fluoropiperidine-4-ylamino)-1H-pyrazolo(3,4-b)pyridin-4-yloxy)-3-fluorophenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide: 1

Experts

1.	Berezhkovskiy, Leonid M: 1 article (04/2011)
2.	Dean, Brian J: 1 article (04/2011)
3.	Dinkel, Vikki: 1 article (04/2011)
4.	Liederer, Bianca M: 1 article (04/2011)
5.	Liu, Xingrong: 1 article (04/2011)
6.	Merchant, Mark: 1 article (04/2011)
7.	Peng, Jing: 1 article (04/2011)
8.	Plise, Emile G: 1 article (04/2011)
9.	Wong, Harvey: 1 article (04/2011)

Related Diseases

1.	Neoplasms (Cancer) 04/01/2011 - "GNE-A (AR00451896; N-(4-(3-((3S,4R)-1-ethyl-3-fluoropiperidine-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-4-yloxy)-3-fluorophenyl)-2-(4-fluorophenyl)-3-oxo-2,3-dihydropyridazine-4-carboxamide) is a potent, selective MET kinase inhibitor being developed as a potential drug for the treatment of human cancers. "

Related Drugs and Biologics

1.	Phosphotransferases (Kinase)