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3-bromoacivicin

antitrypanosomal and a potent CTP synthetase inhibitor; structure in first source

Also Known As:

(alphaS,5S)-alpha-amino-3-bromo-4,5-dihydroisoxazol-5-yl acetic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Isoxazoles: 155
      - 3-bromoacivicin: 1

Experts

1.	Barrett, Michael P: 1 article (02/2011)
2.	Conti, Paola: 1 article (02/2011)
3.	De Micheli, Carlo: 1 article (02/2011)
4.	Iannuzzi, Maria C: 1 article (02/2011)
5.	Major, Louise L: 1 article (02/2011)
6.	Pinto, Andrea: 1 article (02/2011)
7.	Smith, Terry K: 1 article (02/2011)
8.	Tamborini, Lucia: 1 article (02/2011)
9.	Wong, Pui E: 1 article (02/2011)

Related Diseases

1.	Infections 02/07/2011 - "Despite its good in vitro activity and selectivity, 3-bromoacivicin proved to be trypanostatic and failed to completely eradicate the infection when tested in vivo at its maximum tolerable dose."