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DHF 18

an antineoplastic agent; structure in first source

Also Known As:

DHF-18; DHF18 cpd

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        DHF 18: 2
  - Piperazines: 26
    - DHF 18: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavones: 446
        DHF 18: 2

Experts

1.	Chen, Fei-hong: 1 article (01/2011)
2.	Guo, Qing-long: 1 article (01/2011)
3.	Li, Zhi-yu: 1 article (01/2011)
4.	Qiang, Lei: 1 article (01/2011)
5.	Rong, Jing-jing: 1 article (01/2011)
6.	Wu, Tian: 1 article (01/2011)
7.	Wu, Yu-lin: 1 article (01/2011)
8.	Yang, Zhen: 1 article (01/2011)
9.	You, Qi-dong: 1 article (01/2011)
10.	Zhang, Lin-bo: 1 article (01/2011)

Related Diseases

1.	Neoplasms (Cancer) 01/25/2011 - "After the treatment of 40mg/kg DHF-18, the inhibitory rate of tumor weight was 53.69%. " 01/25/2011 - "In this study, we demonstrated that DHF-18 significantly inhibited tumor growth in mice inoculated with Heps hepatoma cells without evident toxicity. " 01/25/2011 - "A new synthetic flavonoid DHF-18, synthesized with a piperazine substitution, has been recently found to show potent anti-tumor activities both in vivo and in vitro. " 01/25/2011 - "To investigate whether apoptosis induction contributed to the anti-tumor effects of DHF-18, DAPI (diamidino-phenyl-indole) staining and Annexin V/PI (Propidium iodide) double staining were performed in our tests. "
2.	Hepatocellular Carcinoma (Hepatoma) 01/25/2011 - "In this study, we demonstrated that DHF-18 significantly inhibited tumor growth in mice inoculated with Heps hepatoma cells without evident toxicity. "
3.	Dengue (Dengue Fever) 10/01/2004 - "Thirty-nine patients had a positive dengue IgM titre, 20 patients had DHF, 18 patients had DSS, and one patient had DF The mean age of presentation was 4.9 years. "

Related Drugs and Biologics

1.	Annexin A5
2.	Propidium (Propidium Iodide)
3.	Immunoglobulin M (IgM)
4.	Flavonoids
5.	Piperazine
6.	indole
7.	DAPI