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immunoRNase scFv 4D5-dibarnase

an antineoplastic agent

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Recombinant Proteins: 2754
    - Recombinant Fusion Proteins: 333
      - immunoRNase scFv 4D5-dibarnase: 2
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Ribonucleases: 2046
        immunoRNase scFv 4D5-dibarnase: 2

Experts

1.	Balandin, Taras G: 2 articles (02/2011 - 06/2008)
2.	Deyev, Sergey M: 2 articles (02/2011 - 06/2008)
3.	Edelweiss, Evelina: 2 articles (02/2011 - 06/2008)
4.	Sapozhnikov, Alexander M: 2 articles (02/2011 - 06/2008)
5.	Andronova, Natalia V: 1 article (02/2011)
6.	Treshalina, Elena M: 1 article (02/2011)
7.	Ivanova, Julia L: 1 article (06/2008)
8.	Leonova, Olga G: 1 article (06/2008)
9.	Lutsenko, Gennady V: 1 article (06/2008)
10.	Popenko, Vladimir I: 1 article (06/2008)

Related Diseases

1.	Neoplasms (Cancer) 06/18/2008 - "Also, we characterized the cytotoxic effects of barnase-based immunoRNase scFv 4D5-dibarnase, which consists of two barnase molecules serially fused to the single-chain variable fragment (scFv) of humanized antibody 4D5 that recognizes the extracellular domain of cancer marker HER2. "
2.	Breast Neoplasms (Breast Cancer) 02/01/2011 - "Antitumor activity and toxicity of anti-HER2 immunoRNase scFv 4D5-dibarnase in mice bearing human breast cancer xenografts."

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