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ozarelix

a synthetic decapeptide, water-soluble LHRH antagonist; structure in first source

Also Known As:

Ac-D-Nal(2)-D-Phe(4Cl)-D-Pal(3)-Ser-NMe-Tyr-D-Hcit-Nle-Arg-Pro-D-Ala-NH2

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Oligopeptides: 519
    - ozarelix: 1

Experts

1.	Dondi, Donatella: 1 article (09/2010)
2.	Festuccia, Claudio: 1 article (09/2010)
3.	Gravina, Giovanni Luca: 1 article (09/2010)
4.	Locatelli, Alessia: 1 article (09/2010)
5.	Motta, Marcella: 1 article (09/2010)
6.	Piccolella, Margherita: 1 article (09/2010)
7.	Tombolini, Vincenzo: 1 article (09/2010)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 09/01/2010 - "This study explored the in vitro effects on DU145 and PC3 cell lines, two models of androgen-independent prostate cancer, of a fourth generation GnRH antagonist (Ozarelix). " 09/01/2010 - "Ozarelix, a fourth generation GnRH antagonist, induces apoptosis in hormone refractory androgen receptor negative prostate cancer cells modulating expression and activity of death receptors."
2.	Neoplasms (Cancer) 09/01/2010 - "TRAIL-resistant cancer cells can be sensitized to TRAIL by Ozarelix. "

Related Drugs and Biologics

1.	Gonadotropin-Releasing Hormone (GnRH)
2.	Androgens
3.	Death Domain Receptors
4.	Androgen Receptors (Androgen Receptor)
5.	Hormones (Hormone)