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N-(4'-dihydro)piperoylthiomorpholine

evokes the Bezold-Jarish reflex; structure in first source

Also Known As:

LASSBio 365; LASSBio-365; LASSBio365

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Oxazines: 9
    - Morpholines: 6
      - N-(4'-dihydro)piperoylthiomorpholine: 1
  - Dioxoles
    - Benzodioxoles: 3
      - N-(4'-dihydro)piperoylthiomorpholine: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzodioxoles: 3
      - N-(4'-dihydro)piperoylthiomorpholine: 1

Experts

1.	Barreiro, Eliezer Jesus: 1 article (09/2010)
2.	Barrès, Christian: 1 article (09/2010)
3.	Julien, Claude: 1 article (09/2010)
4.	Lima, Lídia Moreira: 1 article (09/2010)
5.	Ribeiro, Eurica Adélia Nogueira: 1 article (09/2010)
6.	de Araújo Júnior, João Xavier: 1 article (09/2010)
7.	de Medeiros, Isac Almeida: 1 article (09/2010)

Related Diseases

1.	Hypotension (Low Blood Pressure) 09/01/2010 - "LASSBio 365 [62.5-1000 microg/kg, intravenously (IV)] has potent cardiovascular effects that include hypotension and bradycardia, accompanied by a brief pressor effect and apnea. " 09/01/2010 - "The Bezold-Jarisch reflex (ie, hypotension, bradycardia, and apnea) induced by LASSBio 365 is altered neither by 5-HT3 antagonist (tropisetron, 0.1 mg/kg, intraarterially) nor by the P2x antagonist (PPADS, 8.6 mg/kg, IV). "
2.	Bradycardia 09/01/2010 - "LASSBio 365 [62.5-1000 microg/kg, intravenously (IV)] has potent cardiovascular effects that include hypotension and bradycardia, accompanied by a brief pressor effect and apnea. " 09/01/2010 - "The Bezold-Jarisch reflex (ie, hypotension, bradycardia, and apnea) induced by LASSBio 365 is altered neither by 5-HT3 antagonist (tropisetron, 0.1 mg/kg, intraarterially) nor by the P2x antagonist (PPADS, 8.6 mg/kg, IV). "
3.	Apnea 09/01/2010 - "LASSBio 365 [62.5-1000 microg/kg, intravenously (IV)] has potent cardiovascular effects that include hypotension and bradycardia, accompanied by a brief pressor effect and apnea. " 09/01/2010 - "The Bezold-Jarisch reflex (ie, hypotension, bradycardia, and apnea) induced by LASSBio 365 is altered neither by 5-HT3 antagonist (tropisetron, 0.1 mg/kg, intraarterially) nor by the P2x antagonist (PPADS, 8.6 mg/kg, IV). "

Related Drugs and Biologics

1.	Serotonin 5-HT3 Receptor Antagonists
2.	Tropisetron (Navoban)
3.	pyridoxal phosphate-6-azophenyl-2',4'-disulfonic acid