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Pt2(2-picoline)4(berenil)2

antineoplastic dinuclear platinum complex with berenil and 2-picoline ligands; structure in first source

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - Organoplatinum Compounds
    - Pt2(2-picoline)4(berenil)2: 2
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Picolines: 14
      - Pt2(2-picoline)4(berenil)2: 2

Experts

1.	Ambrożewicz, E: 1 article (01/2013)
2.	Bielawska, A: 1 article (01/2013)
3.	Bielawski, K: 1 article (01/2013)
4.	Gęgotek, A: 1 article (01/2013)
5.	Markowska, A: 1 article (01/2013)
6.	Skrzydlewska, E: 1 article (01/2013)
7.	Łuczaj, W: 1 article (01/2013)
8.	Bielawska, Anna: 1 article (11/2010)
9.	Bielawski, Krzysztof: 1 article (11/2010)
10.	Czarnomysy, Robert: 1 article (11/2010)

Related Diseases

1.

Breast Neoplasms (Breast Cancer)

01/01/2013 - "Results of this paper and preliminary data show that Pt2(2-picoline)4(berenil)2 is less dangers than cisplatin to fibroblasts and more disruptive than cisplatin to breast cancer cell metabolism, and therefore it is a promising candidate for use in future anticancer drug strategies."
11/01/2010 - "Evaluation of the cytotoxicity of a novel dinuclear platinum(II) complex of formula Pt2(2-picoline)4(berenil)2 employing a MTT assay and inhibition of [3H]thymidine incorporation into DNA in both MDA-MB-231 and MCF-7 breast cancer cells demonstrated that the complex was more potent anti-proliferative agent than cisplatin. "

Related Drugs and Biologics

1.	Cisplatin (Platino)
2.	Thymidine
3.	Platinum
4.	DNA (Deoxyribonucleic Acid)