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2- cyclopentyl- N- (2,4- dichloro- 3- ((isoquinolin- 5- yloxy)methyl)phenyl)- N- methylacetamide

a Foxo1 protein inhibitor; structure in first source

Also Known As:

AS 1708727; AS-1708727; AS1708727

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Aniline Compounds: 46
    - Anilides: 22
      - Acetanilides: 7
        2-cyclopentyl-N-(2,4-dichloro-3-((isoquinolin-5-yloxy)methyl)phenyl)-N-methylacetamide: 1
- Amides: 2428
  - Anilides: 22
    - Acetanilides: 7
      - 2-cyclopentyl-N-(2,4-dichloro-3-((isoquinolin-5-yloxy)methyl)phenyl)-N-methylacetamide: 1
Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - 2-cyclopentyl-N-(2,4-dichloro-3-((isoquinolin-5-yloxy)methyl)phenyl)-N-methylacetamide: 1

Experts

1.	Nagashima, Takeyuki: 1 article (10/2010)
2.	Shibasaki, Masayuki: 1 article (10/2010)
3.	Shimaya, Akiyoshi: 1 article (10/2010)
4.	Shimokawa, Teruhiko: 1 article (10/2010)
5.	Tanaka, Hirotsugu: 1 article (10/2010)
6.	Urano, Yasuharu: 1 article (10/2010)

Related Diseases

1.	Hypertriglyceridemia 10/25/2010 - "These results indicate that the novel Foxo1 inhibitor AS1708727 may exert anti-diabetic and anti-hypertriglyceridemic effects by improving blood glucose and triglyceride metabolism at the gene expression level, and may represent a new class of drugs useful for treating type 2 diabetes mellitus and hypertriglyceridemia."
2.	Type 2 Diabetes Mellitus (MODY) 10/25/2010 - "These results indicate that the novel Foxo1 inhibitor AS1708727 may exert anti-diabetic and anti-hypertriglyceridemic effects by improving blood glucose and triglyceride metabolism at the gene expression level, and may represent a new class of drugs useful for treating type 2 diabetes mellitus and hypertriglyceridemia."

Related Drugs and Biologics

1.	Triglycerides (Triacylglycerol)
2.	Blood Glucose (Blood Sugar)