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4- (4- (4- fluorophenyl)thiazol- 2- ylamino)- 2,6- dimethylphenol

a 5-lipoxygenase inhibitor and anti-inflammatory agent; structure in first source

Also Known As:

KR 33749; KR-33749; KR33749

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Xylenes: 648
        4-(4-(4-fluorophenyl)thiazol-2-ylamino)-2,6-dimethylphenol: 1
- Sulfur Compounds: 278
  - Thiazoles: 392
    - 4-(4-(4-fluorophenyl)thiazol-2-ylamino)-2,6-dimethylphenol: 1
Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Thiazoles: 392
      - 4-(4-(4-fluorophenyl)thiazol-2-ylamino)-2,6-dimethylphenol: 1

Experts

1.	Cheon, Hyae Gyeong: 1 article (01/2010)
2.	Cho, Young Sik: 1 article (01/2010)
3.	Kang, Nam Sook: 1 article (01/2010)
4.	Kim, Chi Hyun: 1 article (01/2010)
5.	Surh, Ji Hee: 1 article (01/2010)
6.	Yoo, Sung-Eun: 1 article (01/2010)

Related Diseases

1.	Edema (Dropsy) 01/01/2010 - "KR-33749 showed in vivo protective effects against arachidonic acid-induced ear edema and DNCB-induced atopic dermatitis-like symptoms in NC/Nga mice. "
2.	Atopic Dermatitis (Atopic Eczema) 01/01/2010 - "KR-33749 showed in vivo protective effects against arachidonic acid-induced ear edema and DNCB-induced atopic dermatitis-like symptoms in NC/Nga mice. "
3.	Skin Diseases (Skin Disease) 01/01/2010 - "To discover new 5-lipoxygenase (5-LO) inhibitors applicable to inflammation-related skin disease, we identified and examined antiinflammatory properties of a novel 5-LO inhibitor, KR-33749, in vitro and in vivo. "
4.	Inflammation (Inflammations) 01/01/2010 - "To discover new 5-lipoxygenase (5-LO) inhibitors applicable to inflammation-related skin disease, we identified and examined antiinflammatory properties of a novel 5-LO inhibitor, KR-33749, in vitro and in vivo. "

Related Drugs and Biologics

1.	Arachidonic Acid (Vitamin F)
2.	Dinitrochlorobenzene (DNCB)
3.	Arachidonate 5-Lipoxygenase (5 Lipoxygenase)