shenkang

01/06/2021 - "As a commonly used herbal formula, Shenkang (SK) has been found to attenuate renal fibrosis and renal parenchyma destruction. "
01/06/2021 - "Effect of Shenkang on renal fibrosis and activation of renal interstitial fibroblasts through the JAK2/STAT3 pathway."
12/01/2023 - "After treatment with Shenkang injection, all indexes in the administered group improved and showed significant inhibition of renal cell fibrosis in vitro. "
10/01/2020 - "This study aimed to explore the protective effects of the traditional Chinese Medicine formula Shenkang VII recipe (SK-7) on renal fibrosis and the mechanisms. "
01/01/2021 - "Shenkang injection (SKI) has been widely used to treat renal tubulointerstitial fibrosis in patients with chronic kidney disease in China. "

01/01/2022 - "Previous studies have shown that Shenkang injection can prevent and treat chronic kidney disease through multiple channels of action. "
01/10/2020 - "Prediction of the mechanisms of action of Shenkang in chronic kidney disease: A network pharmacology study and experimental validation."
08/01/2015 - "The purpose of this study is to investigate the antifibrosis and antioxidation of ShenKang injection (SKI) in vivo and in vitro and to evaluate potential mechanisms involved in the treatment of chronic kidney disease (CKD). "
01/01/2022 - "However, the precise relationship between Shenkang injection and the regulation of the TGF-/Smads signaling pathway in the treatment of chronic kidney disease is unknown. "
12/01/2020 - "A review on the efficacy and mechanism of action of Shenkang injection against chronic kidney disease."

09/01/2023 - "Network pharmacology-based study on the mechanism of ShenKang injection in diabetic kidney disease through Keap1/Nrf2/Ho-1 signaling pathway."
01/01/2022 - "Effects of Shenkang Pills on Early-Stage Diabetic Nephropathy in db/db Mice via Inhibiting AURKB/RacGAP1/RhoA Signaling Pathway."
12/24/2020 - "RCTs assessing Shenkang injection combined with basic treatments versus basic treatments alone for treating diabetic nephropathy will be included. "
12/24/2020 - "We will systematically review the current randomized controlled trial (RCT) evidence to summarize the efficacy and safety of Shenkang injection in treating diabetic nephropathy. "
08/01/2014 - "This finding provides a new theoretical basis for the application of Shenkang pill to treat diabetic nephropathy."

01/01/2023 - "Study on the mechanism of Shenkang injection in the treatment of chronic renal failure based on the strategy of "Network pharmacology-Molecular docking-Key target validation"."
12/01/2023 - "Pharmacokinetic-pharmacodynamic modeling of the active components of Shenkang injection in rats with chronic renal failure and its protective effect on damaged renal cells."
12/03/2021 - "Efficacy and safety of Shenkang injection in the treatment of chronic renal failure: A protocol of a randomized controlled trial."
10/01/2018 - "Shenkang injection is a traditional Chinese formula with good curative effect on chronic renal failure. "
06/01/2015 - "Effect of Shenkang granules on the progression of chronic renal failure in 5/6 nephrectomized rats."

01/01/2023 - "To explore the potential mechanism of Shenkang injection (SKI) in the treatment of chronic renal failure based on network pharmacology and molecular docking technology, and to verify the core targets and key pathways by using the renal failure model. "
10/01/2016 - "[Effects and mechanisms of Shenkang injection promoting extracellular matrix degradation via regulating ERK1/2/MMPs signaling pathway in renal failure rats]."
10/01/2016 - "This study aimed to clarify preliminarily the effects and mechanisms of Shenkang injection (SKI) promoting extracellular matrix(ECM)degradation via regulating extracellular-signal regulated protein kinase(ERK)1/2/matrix metalloproteinases(MMPs)signaling pathway in renal failure rats. "