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2- (2- fluoro- 4- (pyrrolidin- 2- yl)phenyl)- 1H- benzimidazole- 4- carboxamide

structure in first source

Also Known As:

A 966492; A-966492; A966492

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzimidazoles: 245
      - 2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide: 2

Experts

1.	Eynali, Samira: 2 articles (11/2021 - 01/2017)
2.	Eyvazzadeh, Nazila: 2 articles (11/2021 - 01/2017)
3.	Koosha, Fereshteh: 2 articles (11/2021 - 01/2017)
4.	Kamalabadi, Mahdieh Ahmadi: 1 article (11/2021)
5.	Mazaheri, Zohreh: 1 article (01/2017)
6.	Mousavi, Mehdi: 1 article (01/2017)
7.	Neshasteh-Riz, Ali: 1 article (01/2017)
8.	Takavar, Abbas: 1 article (01/2017)

Related Diseases

1.

Glioblastoma (Glioblastoma Multiforme)

01/01/2017 - "The combination of A-966492 and Topotecan for effective radiosensitization on glioblastoma spheroids."
11/01/2021 - "The effect of iodine-131 beta-particles in combination with A-966492 and Topotecan on radio-sensitization of glioblastoma: An in-vitro study."
11/01/2021 - "In the present research, the impact of beta-particles of iodine-131 in combination with Topotecan (TPT), as the inhibitor of topoisomerase I, and A-966492, as the inhibitor of the PARP enzyme on the possible increase of radio-sensitivity of glioblastoma cells was assessed. "

Related Drugs and Biologics

1.	Topotecan (Hycamtin)
2.	Iodine-131
3.	Enzymes
4.	Type I DNA Topoisomerases (Topoisomerase I)
5.	9 alpha,11 alpha,15 alpha- trihydroxy- 16- phenoxy- 17,18,19,20- tetranorprosta- 4,5,13- trienoic acid (TPT)