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hemoglobin Southern Italy

proline replaces alanine at position 130 of alpha chain and threonine replaces alanine at position 26 of the alpha chain

Also Known As:

Hb Southern Italy

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Hemoglobins: 37188
      - Abnormal Hemoglobins: 120
        hemoglobin Southern Italy: 1
  - Hemeproteins: 194
    - Globins: 2716
      - Hemoglobins: 37188
        Abnormal Hemoglobins: 120
        hemoglobin Southern Italy: 1

Experts

1.	Caldora, Mercedes: 1 article (01/2020)
2.	Cardiero, Giovanna: 1 article (01/2020)
3.	Colella Bisogno, Rosario: 1 article (01/2020)
4.	Di Girgenti, Caterina: 1 article (01/2020)
5.	Friscia, Maria Grazia: 1 article (01/2020)
6.	Gaudiano, Carlo: 1 article (01/2020)
7.	Lacerra, Giuseppina: 1 article (01/2020)
8.	Manco, Giuseppe: 1 article (01/2020)
9.	Musollino, Gennaro: 1 article (01/2020)
10.	Testa, Rosario: 1 article (01/2020)

Related Diseases

1.	Thalassemia 01/01/2020 - "For Hb Southern Italy, showing an unexpected α/β biosynthetic ratio typical of the β-thalassemia type, two different molecular mechanisms were shown: Reduction of the variant mRNA, likely due to the No-Go Decay for the presence of unused triplet ACG at cod 26, and protein instability due to the impairment of AHSP interaction. "

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