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ethyl 4-methoxycinnamate

an antifungal agent isolated from Curcumba zedoaria

Also Known As:

ethyl p-methoxycinnamate

Networked: 12 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Carbocyclic Acids
    - Cinnamates: 48
      - ethyl 4-methoxycinnamate: 12

Experts

1.	Na-Bangchang, Kesara: 2 articles (07/2020 - 04/2020)
2.	Hardianti, Besse: 1 article (02/2022)
3.	Hayakawa, Yoshihiro: 1 article (02/2022)
4.	Ismail, Ismail: 1 article (02/2022)
5.	Laela, Dewi: 1 article (02/2022)
6.	Lallo, Subehan: 1 article (02/2022)
7.	Sartini, Sartini: 1 article (02/2022)
8.	Plengsuriyakarn, Tullayakorn: 1 article (07/2020)
9.	Tarasuk, Mayuri: 1 article (07/2020)
10.	Tritripmongkol, Porwornwisit: 1 article (07/2020)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 02/24/2022 - "Among the isolated compounds, ethyl p-methoxycinnamate (EPMC) demonstrated potent NFκB inhibitory activity against melanoma cell B16F10- NFκB Luc2 with an IC50 of 88.7 μM. " 02/24/2022 - "Ethyl P-Methoxycinnamate: An Active Anti-Metastasis Agent and Chemosensitizer Targeting NFκB from Kaempferia galanga for Melanoma Cells." 02/01/2014 - "In the present study, we found that ethyl p-methoxycinnamate significantly decreased melanin synthesis in B16F10 murine melanoma cells stimulated with α-melanocyte stimulating hormone (α-MSH). "
2.	Vector Borne Diseases 08/01/2008 - "Kaempferia galanga rhizome-derived materials, particularly ethyl p-methoxycinnamate, merit further study as potential mosquito control agents for protection of humans and domestic animals from vector-borne diseases and nuisance caused by mosquitoes."
3.	Cholangiocarcinoma 07/01/2020 - "and its active component, ethyl-p-methoxycinnamate, against cholangiocarcinoma." 04/01/2020 - "Cytotoxicity, Cell Cycle Arrest, and Apoptosis Induction Activity of Ethyl-p-methoxycinnamate in Cholangiocarcinoma Cell." 04/01/2020 - "To investigate cytotoxic activity of ethyl-p-methoxycinnamate (EPMC) including its effect on p-glycoprotein (multidrug resistance-1: mdr-1 gene) in human cholangiocarcinoma cell. "
4.	Tuberculosis (Tuberculoses) 07/01/2011 - "Ethyl p-methoxycinnamate isolated from a traditional anti-tuberculosis medicinal herb inhibits drug resistant strains of Mycobacterium tuberculosis in vitro."
5.	Psoriasis (Pustulosis Palmaris et Plantaris) 01/01/2023 - "HaCaT and peripheral blood mononuclear cells (PBMCs) from healthy volunteers (n = 9) and psoriasis patients (n = 10) were exposed to Deprungsith formulation (Thai traditional medicine for psoriasis consisting of 16 plants), ethyl p-methoxycinnamate (EPMC), ligustilide and cyclosporin for 24 and 48 h. "

Related Drugs and Biologics

1.	Melanocyte-Stimulating Hormones (MSH)
2.	Melanins (Melanin)
3.	Member 1 Subfamily B ATP Binding Cassette Transporter
4.	Neuroprotective Agents
5.	Cyclosporine (Ciclosporin)
6.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
7.	Interleukin-1 (Interleukin 1)
8.	Croton Oil
9.	Aluminum
10.	Acids

Related Therapies and Procedures

1.	Thai Traditional Medicine