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manganese(II)(N,N- bis(2- pyridylmethyl)amine- N- ethyl- 2- quinoline- 2- carboxamide)

structure in first source

Also Known As:

(Mn(PaPy2Q)(NO))ClO4

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organometallic Compounds: 64
  - manganese(II)(N,N-bis(2-pyridylmethyl)amine-N-ethyl-2-quinoline-2-carboxamide): 1

Experts

1.	Ao, Zhixian: 1 article (05/2021)
2.	Chen, Lixin: 1 article (05/2021)
3.	Huang, Yunsheng: 1 article (05/2021)
4.	Li, Jianwei: 1 article (05/2021)
5.	Li, Zhuo: 1 article (05/2021)
6.	Lin, Shanhong: 1 article (05/2021)
7.	Liu, Jianjun: 1 article (05/2021)
8.	Luo, Qiuming: 1 article (05/2021)
9.	Mo, Jierong: 1 article (05/2021)
10.	Tang, Huancheng: 1 article (05/2021)

Related Diseases

1.	Prostatic Neoplasms (Prostate Cancer) 05/01/2021 - "Next, the results in xenograft mouse model showed that [Mn(PaPy2Q)(NO)]ClO4 also had anti-prostate cancer effects in vivo, and the NO concentration increased in the tumor after near-infrared light irradiation. " 05/01/2021 - "Then we also found that [Mn(PaPy2Q)(NO)]ClO4 increased the expression of apoptosis-related proteins (PARP, Bax, Caspase 3/9), inhibited the expression of BCl-2 and increased the activity level of Caspase 3/7, which showed [Mn(PaPy2Q)(NO)]ClO4 promoted prostate cancer cells apoptosis. " 05/01/2021 - "[Mn(PaPy2Q)(NO)]ClO4, a Near-Infrared Light activated release of Nitric Oxide drug as a nitric oxide donor for therapy of human prostate cancer cells in vitro and in vivo."
2.	Neoplasms (Cancer) 05/01/2021 - "TUNEL assay results showed that [Mn(PaPy2Q)(NO)]ClO4 could promote the apoptosis of solid tumors in vivo and in a concentration-dependent manner." 05/01/2021 - "Next, the results in xenograft mouse model showed that [Mn(PaPy2Q)(NO)]ClO4 also had anti-prostate cancer effects in vivo, and the NO concentration increased in the tumor after near-infrared light irradiation. " 05/01/2021 - "After [Mn(PaPy2Q)(NO)]ClO4 treatment 6 weeks, tumor volume was significantly reduced, Ki67 and BrdU protein expression was significantly reduced. "

Related Drugs and Biologics

1.	Caspase 3 (Caspase-3)
2.	Nitric Oxide Donors
3.	Proteins (Proteins, Gene)
4.	Nitric Oxide (Nitrogen Monoxide)
5.	Bromodeoxyuridine (BrdU)

Related Therapies and Procedures

1.	Therapeutics