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cudraflavanone A

antineoplastic from Cudrania tricuspidata; structure in first source

Also Known As:

2S-2',5,7-trihydroxy-4',5'-(2,2-dimethylchromeno)-6-prenyl flavanone

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavanones: 184
        cudraflavanone A: 3
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Chromones: 159
        Flavonoids: 9773
        Flavanones: 184
        cudraflavanone A: 3

Experts

1.	Kim, Dong-Cheol: 1 article (12/2018)
2.	Kim, Kwan-Woo: 1 article (12/2018)
3.	Kim, Youn-Chul: 1 article (12/2018)
4.	Ko, Wonmin: 1 article (12/2018)
5.	Oh, Hyuncheol: 1 article (12/2018)
6.	Quang, Tran Hong: 1 article (12/2018)
7.	Yoon, Chi-Su: 1 article (12/2018)
8.	Bae, Young-Seuk: 1 article (10/2007)
9.	Lee, Byong-Won: 1 article (10/2007)
10.	Park, Ki-Hun: 1 article (10/2007)

Related Diseases

1.	Neuroinflammatory Diseases 12/01/2018 - "The present study suggests a potent effect of cudraflavanone A to prevent neuroinflammatory diseases. "
2.	Atherosclerosis 09/01/2007 - "Selective modification of Akt activation by cudraflavanone A in VSMCs may suppress intimal thickening after angioplasty and plaque formation in atherosclerosis. " 09/01/2007 - "tricuspidata may be useful in the prevention of atherosclerosis or restenosis after angioplasty, we investigated the ability of cudraflavanone A to inhibit VSMCs growth under 25 ng/mL platelet-derived growth factor BB (PDGF-BB)-stimulated conditions. "
3.	Neoplasms (Cancer) 10/01/2007 - "A concentration of 6 micromol/l cudraflavanone A caused a 50% growth inhibition of human cancer cell U937. "
4.	Leukemia 10/01/2007 - "Cudraflavanone A purified from Cudrania tricuspidata induces apoptotic cell death of human leukemia U937 cells, at least in part, through the inhibition of DNA topoisomerase I and protein kinase C activity."

Related Drugs and Biologics

1.	Protein Kinase C
2.	Type I DNA Topoisomerases (Topoisomerase I)
3.	Becaplermin (PDGF-BB)