SAK-RGD-K2-Hir

antithrombotic chimeric protein composed of staphylokinase, RGD peptide, K2 domain, and hirudin

Networked: 2 relevant articles (0 outcomes, 1 trials/studies)

1.	Chabielska, Ewa: 2 articles (01/2011 - 06/2007)
2.	Gromotowicz, Anna: 2 articles (01/2011 - 06/2007)
3.	Stankiewicz, Adrian: 2 articles (01/2011 - 06/2007)
4.	Szemraj, Janusz: 2 articles (01/2011 - 06/2007)
5.	Brown, George: 1 article (01/2011)
6.	Grędziński, Tomasz: 1 article (01/2011)
7.	Zakrzeska, Agnieszka: 1 article (01/2011)
8.	Bartkowiak, Jacek: 1 article (06/2007)
9.	Buczko, Wlodzimierz: 1 article (06/2007)
10.	Mogielnicki, Andrzej: 1 article (06/2007)

1.	Carotid Artery Thrombosis 01/01/2011 - "The aim of the present study was to examine the thrombolytic potentials of SAK-RGD-K2-Hir and SAK-RGD-K2-Hirul in an electrically induced carotid artery thrombosis model in rats and to compare the potentials to that of r-SAK. " 06/01/2007 - "In order to document the effects of the thrombolytic potential of SAK-RGD-K2-Hir we examined this protein in an electrically induced carotid artery thrombosis model and stasis-induced venous model in rats. "
2.	Thrombosis (Thrombus) 06/01/2007 - "In the arterial thrombosis model, a bolus injection of SAK-RGD-K2-Hir was less effective than rt-PA and r-SAK. " 01/01/2011 - "We determined that a bolus injection of SAK-RGD-K2-Hirul was more effective than one of r-SAK in the improvement and maintenance of carotid patency and in arterial thrombus weight reduction; however, it had the same potency as SAK-RGD-K2-Hir. "
3.	Weight Loss (Weight Reduction) 01/01/2011 - "We determined that a bolus injection of SAK-RGD-K2-Hirul was more effective than one of r-SAK in the improvement and maintenance of carotid patency and in arterial thrombus weight reduction; however, it had the same potency as SAK-RGD-K2-Hir. "
4.	Hemorrhage 06/01/2007 - "Furthermore, our results also suggest that SAK-RGD-K2-Hir bears a risk of bleeding, but this may be true for higher doses."