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diguanidine

structure in first source

Also Known As:

DB711

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Furans: 85
    - diguanidine: 4
Organic Chemicals: 133
- Amidines: 14
  - Guanidines: 29
    - Guanidine: 777
      - diguanidine: 4

Experts

1.	Boykin, D W: 1 article (11/2007)
2.	De Souza, E M: 1 article (11/2007)
3.	Meirelles, M N L: 1 article (11/2007)
4.	Meuser, M B: 1 article (11/2007)
5.	Silva, C F: 1 article (11/2007)
6.	Soeiro, M N C: 1 article (11/2007)
7.	Som, P: 1 article (11/2007)
8.	Stephens, C E: 1 article (11/2007)

Related Diseases

1.	Ascites 12/15/1980 - "Ascites-tumour cells deprived of putrescine and spermidine likewise concentrated methylglyoxal bis(guanylhydrazone) [1,1'-[methylethanedylidine)dinitrilo]diguanidine] at a greatly enhanced rate. " 05/15/1980 - "The anti-proliferative effects of 1,1'-[(methylethanediylidene)dinitrilo]diguanidine [methylglyoxal bis(guanylhydrazone)] and 1,1'-[(metHYLETHANEDIYLIDENE)dinitrilo]bis-(3-aminoguaNIDINE) HAVE BEEN STUDIED IN Ehrlich ascites carcinoma cells grown in suspension cultures. "
2.	Chagas Disease (American Trypanosomiasis) 11/01/2007 - "Since the chemotherapy for Chagas' disease is still an unsolved problem and previous reports on diamidines and related analogues show that they have high levels of activity against Trypanosoma cruzi infection both in vitro and in vivo, our present aim was to evaluate the cellular effects in vitro of three reversed amidines (DB889, DB702, and DB786) and one diguanidine (DB711) against both amastigotes and bloodstream trypomastigotes of T. "
3.	Trypanosomiasis 07/01/1949 - "Experimental chemotherapy of trypanosomiasis; effect of p-phenylene diguanidine and related compounds against experimental infections with Trypanosoma equiperdum."
4.	Infections 07/01/1949 - "Experimental chemotherapy of trypanosomiasis; effect of p-phenylene diguanidine and related compounds against experimental infections with Trypanosoma equiperdum."
5.	Carcinoma (Carcinomatosis) 05/15/1980 - "The anti-proliferative effects of 1,1'-[(methylethanediylidene)dinitrilo]diguanidine [methylglyoxal bis(guanylhydrazone)] and 1,1'-[(metHYLETHANEDIYLIDENE)dinitrilo]bis-(3-aminoguaNIDINE) HAVE BEEN STUDIED IN Ehrlich ascites carcinoma cells grown in suspension cultures. "

Related Drugs and Biologics

1.	Mitoguazone (MGBG)
2.	diguanidine
3.	Suspensions
4.	Spermidine
5.	Putrescine
6.	Amidines
7.	pimagedine (aminoguanidine)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)