davanone

antifungal and antispasmodic isolated from natural Davana oil and Artemisia pallens; structure in first source

Networked: 2 relevant articles (1 outcomes, 1 trials/studies)

1.	Ovarian Neoplasms (Ovarian Cancer) 09/01/2020 - "The current study was undertaken to examine the anticancer potential of davanone against human ovarian cancer cells along with evaluating its effects on cell apoptosis, PI3K/AKT/MAPK signaling pathway and cell migration and invasion. " 09/01/2020 - "Naturally occurring davanone terpenoid exhibits anticancer potential against ovarian cancer cells by inducing programmed cell death, by inducing caspase-dependent apoptosis, loss of mitochondrial membrane potential, inhibition of cell migration and invasion and targeting PI3K/AKT/MAPK signaling pathway." 09/01/2020 - "The results indicate that davanone is a potential anticancer agent against human ovarian cancer mediated via caspase-dependent apoptosis, loss of MMP, inhibition of cell migration and invasion and targeting PI3K/AKT/MAPK signaling pathway."
2.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/01/2020 - "Davanone terpenoid inhibits cisplatin-resistant acute myeloid leukemia cancer cell growth by inducing caspase-dependent apoptosis, loss of mitochondrial membrane potential, inhibition of cell migration and invasion and targeting PI3K/AKT/MAPK signalling pathway."
3.	Neoplasms (Cancer) 05/01/2020 - "Davanone terpenoid inhibits cisplatin-resistant acute myeloid leukemia cancer cell growth by inducing caspase-dependent apoptosis, loss of mitochondrial membrane potential, inhibition of cell migration and invasion and targeting PI3K/AKT/MAPK signalling pathway."

1.	Terpenes (Terpenoids)
2.	Matrix Metalloproteinases (MMPs)
3.	Cisplatin (Platino)
4.	Antineoplastic Agents (Antineoplastics)