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gymnemagenin

isolated from Gymnema sylvestre

Also Known As:

Olean-12-ene-3,16,21,22,23,28-hexol, (3beta,16beta,21beta,22alpha)-

Networked: 3 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Alkaloids: 5398
  - gymnemagenin: 3

Experts

1.	Arunachalam, Kantha Devi: 1 article (01/2022)
2.	Madhavan, Thirumurthy: 1 article (01/2022)
3.	Nagarajan, Santhosh Kumar: 1 article (01/2022)
4.	R Jayakumar, Arumugam: 1 article (01/2022)
5.	Saiyad Musthafa, Mohamed: 1 article (01/2022)
6.	Sinha, Pamela: 1 article (01/2022)

Related Diseases

1.	Obesity 01/01/2022 - "In silico study revealed that gymnemagenin targeted 12 genes were modulating 6 molecular pathways involved in diabetes and obesity. " 01/01/2022 - "Conclusion: Gymnemagenin improved lipid metabolism by increasing triglyceride hydrolysis (lipolysis), up regulating the crucial gene of adipogenesis and increasing the expression of anti-inflammatory adipokine proving its therapeutic importance as anti-obesity and anti-diabetic phytocompound."
2.	Body Weight (Weight, Body) 01/01/2022 - "The radioprotective efficacy of Gymnema sylvestre leaves extract (GS) [25 mg/kg Body Weight (B.W)] and its bioactive compound Gymnemagenin (GG) [0.3 mg/kg B.W] was compared with Amifostine (Ami), the only radioprotector clinically approved by the US-FDA [Ami- 83.3 mg/kg B.W] against different doses of gamma radiation - 60Co (Lethal Dose: LD30-9.2 Gy, LD50-10.2 Gy and LD70-11.4 Gy). "
3.	Type 2 Diabetes Mellitus (MODY) 01/01/2022 - "Elucidating type 2 diabetes mellitus risk factor by promoting lipid metabolism with gymnemagenin: An in vitro and in silico approach."
4.	Acquired Immunodeficiency Syndrome (AIDS) 01/01/2023 - "Of these, 139 patents for antidiabetic therapeutic aids that included berberine, curcumin, gingerol, gymnemic acid, gymnemagenin and mangiferin were analyzed. "

Related Drugs and Biologics

1.	Adipokines
2.	Triglycerides (Triacylglycerol)
3.	Amifostine (Ethyol)
4.	Hypoglycemic Agents (Hypoglycemics)
5.	Curcumin
6.	Berberine
7.	mangiferin
8.	gymnemic acid
9.	gingerol