9- dimethylamino- 3- (4- ethylphenyl)- 3H- 5- thia- 1,3,6- triazafluoren- 4- one
an mGluR1 antagonist; structure in first source
Also Known As:
9-dimethylamino-ETTO; A 794282; A-794282; A794282
Networked: 1
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
1. | Baker, Scott:
1 article
(02/2008)
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2. | Brioni, Jorge D:
1 article
(02/2008)
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3. | Chang, Renjie:
1 article
(02/2008)
|
4. | EI-Kouhen, Odile:
1 article
(02/2008)
|
5. | Gauvin, Donna M:
1 article
(02/2008)
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6. | Hernandez, Gricelda:
1 article
(02/2008)
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7. | Hollingsworth, Peter R:
1 article
(02/2008)
|
8. | Honore, Prisca:
1 article
(02/2008)
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9. | Lehto, Sonya G:
1 article
(02/2008)
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10. | Moreland, Robert B:
1 article
(02/2008)
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Related Diseases
1. | Postoperative Pain
02/12/2008
- " In the present study, effects of potent and selective mGlu1 receptor antagonists A-841720, A-794282, A-794278, and A-850002 were evaluated in a skin incision-induced post-operative pain model in rats. " 02/12/2008
- " In this model, A-841720, A-794282, A-794278, and A-850002 induced significant attenuation of spontaneous post-operative pain behavior, with ED50s of 10, 50, 50, and 65 micromol/kg i.p., respectively. "
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