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prunustatin A

inhibits expression of GRP78; isolated from Streptomyces violaceoniger; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Lactones: 1549
  - Macrolides: 4391
    - prunustatin A: 1
  - Polyketides: 231
    - Macrolides: 4391
      - prunustatin A: 1
Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Polyketides: 231
    - Macrolides: 4391
      - prunustatin A: 1

Experts

1.	Chijiwa, Shuhei: 1 article (03/2005)
2.	Furihata, Kazuo: 1 article (03/2005)
3.	Furihata, Keiko: 1 article (03/2005)
4.	Nagasawa, Hiromichi: 1 article (03/2005)
5.	Sakuda, Shohei: 1 article (03/2005)
6.	Shin-ya, Kazuo: 1 article (03/2005)
7.	Umeda, Yukiko: 1 article (03/2005)
8.	Watanabe, Hidenori: 1 article (03/2005)

Related Diseases

1.	Fibrosarcoma 03/01/2005 - "Prunustatin A inhibited the expression of GRP78 induced by 2-deoxyglucose in human fibrosarcoma HT1080 cells accompanied by global cell death without showing cytotoxicity under normal nutrient condition."

Related Drugs and Biologics

1.	Deoxyglucose (2 Deoxy D glucose)
2.	Endoplasmic Reticulum Chaperone BiP