dihydrate dibasic calcium phosphate (brushite)

Molecular formula CaHPO(4)-2(H2O)

Also Known As:

brushite; calcium phosphate, dibasic, dihydrate; calcium monohydrogen phosphate dihydrate; calcium phosphate, dibasic; calcium phosphate, dihydrate (1:1); dibasic calcium phosphate dihydrate; dicalcium phosphate; dicalcium phosphate anhydrous; dicalcium phosphate dihydrate; CaHPO(4)-2(H2O)

Networked: 186 relevant articles (8 outcomes, 25 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Inorganic Chemicals: 9

Experts

1.	Lingeman, James E: 11 articles (05/2020 - 06/2003)
2.	Evan, Andrew P: 9 articles (05/2020 - 02/2005)
3.	Coe, Fredric L: 8 articles (06/2021 - 02/2005)
4.	Worcester, Elaine M: 7 articles (06/2021 - 02/2005)
5.	Krambeck, Amy E: 6 articles (01/2021 - 08/2010)
6.	Daudon, Michel: 5 articles (12/2022 - 11/2004)
7.	Williams, James C: 5 articles (05/2020 - 06/2003)
8.	Bossert, Jörg: 4 articles (09/2019 - 11/2017)
9.	Gunnella, Francesca: 4 articles (09/2019 - 11/2017)
10.	Horbert, Victoria: 4 articles (09/2019 - 11/2017)

Related Diseases

1.	Urinary Calculi (Urinary Calculus) 10/01/2010 - "From 1996 to 2008 we identified 82 patients with brushite urinary calculi. " 12/01/2004 - "Correlation was sought between stone events and urinary stone risk factors, and between brushite and urinary constituent RSRs before and after adjustment for variables. " 04/01/1991 - "The clinical history of 30 patients with a total of 46 proved brushite urinary calculi was reviewed. " 11/24/2021 - "Dicalcium phosphate dihydrate (DCPD; CaPO4·2H2O), along with other significant CaP phases, have been observed in pathogenic calcifications such as dental calculi, kidney stones and urinary stones. " 01/01/2006 - "Vickers hardness studies of calcium oxalate monohydrate and brushite urinary stones."
2.	Hypercalciuria 10/01/2010 - "All patients with brushite stones in this cohort had an underlying metabolic abnormality and specifically brushite stones should be heralded as a marker for hypercalciuria. " 07/01/2009 - "Under normocalciuria conditions, new COM crystals formed; both COM and COD crystals developed under hypercalciuria conditions at a urinary pH < 6.0; and in hypercalciuric conditions and urinary pH > 6.0 both HAP and brushite (BRU) crystals were formed. " 01/01/1985 - "In the 24 h-urine of HPT hypercalciuria and increased saturation with respect to brushite which reached values to induce HAP crystallization were found. " 07/01/2006 - "Lower body negative pressure chamber treadmill exercise offers some protection against increases in stone risk during simulated microgravity, particularly with regard to the risks of hypercalciuria and brushite stone formation. " 01/01/2013 - "Hypercalciuria, a diminished citrate excretion and an elevated pH turned out to be the major urinary determinants of brushite stone formation. "
3.	Shock 08/01/2010 - "Studies have demonstrated an association between brushite stone disease and shock wave lithotripsy (SWL) treatment. " 09/01/2012 - "Thus, current diagnostic computerized tomography technology does not provide a means to predict when brushite stones will break well using shock wave lithotripsy." 09/01/2012 - "The shock wave lithotripsy fragility of brushite stones did not correlate with internal structure discernible on helical computerized tomography. " 09/01/2012 - "Brushite stones were imaged in vitro and then broken with shock wave lithotripsy to assess whether stone fragility correlates with internal stone structure visible on helical computerized tomography. " 09/01/2012 - "Fragility of brushite stones in shock wave lithotripsy: absence of correlation with computerized tomography visible structure."
4.	Dental Calculus 02/01/1983 - "Brushite was unexpectedly rare, and no calcite was detected in any portion of human dental calculus. " 02/01/1983 - "The mechanism of the formation of dental calculus being considered in this paper is that octacalcium phosphate or brushite is formed during the initial stage of calcification of dental plaque, and is gradually hydrolyzed and transformed into hydroxyapatite and/or whitlockite." 01/01/1998 - "In the second organoleptic study, a dentifrice containing 65% baking soda demonstrated significantly greater ability to reduce breath odor than a standard sodium fluoride/silica tartar control dentifrice, but did not differ significantly from a standard dentifrice containing 0.76% sodium monofluorophosphate in a dicalcium phosphate dihydrate base. " 01/01/2002 - "Brushite, dicalcium phosphate dihydrate, octacalcium phosphate, hydroxyapatite, and whitlockite form the mineral part of dental calculus. " 01/01/1994 - "The effect of a dentifrice containing 5.0% potassium nitrate, 1.3% soluble pyrophosphate, 1.5% PVM/MA copolymer, and 0.243% sodium fluoride in a silica base (Sensitive/Tartar Control) on dentinal hypersensitivity over a twelve-week period was compared to a commercially available dentifrice containing 5% potassium nitrate and 0.76% sodium monofluorophosphate in a dicalcium phosphate dihydrate base (Sensodyne-F). "
5.	Dentin Sensitivity 04/18/2023 - "The aim of this study was the evaluation of the in vitro efficacy of a carbon dioxide (CO2) laser, a tetracalcium phosphate/dicalcium phosphate anhydrate (TP/DP) desensitizer and the combination of the desensitizer and additional CO2 laser irradiation as a treatment modality for cervical dentin hypersensitivity. " 06/01/2000 - "To investigate the relative effectiveness provided by a new dentifrice containing 5.0% potassium nitrate and 0.454% stannous fluoride in a silica base (Colgate Sensitive Maximum Strength dentifrice) for reducing dentin hypersensitivity over an 8-wk period, as compared to that provided by a commercially-available antihypersensitivity dentifrice containing 5.0% potassium nitrate and 0.76% sodium monofluorophosphate in a dicalcium phosphate base (Fresh Mint Sensodyne dentifrice). " 06/01/2000 - "To evaluate the relative effectiveness provided by a new dentifrice containing 5.0% potassium nitrate and 0.454% stannous fluoride in a silica base (Colgate Sensitive Maximum Strength) for reducing dentin hypersensitivity over an 8-wk period, as compared to that provided by a commercially-available antihypersensitivity dentifrice containing 5.0% potassium nitrate and 0.76% sodium monofluorophosphate in a dicalcium phosphate base (Fresh Mint Sensodyne dentifrice). "

Related Drugs and Biologics

1.	Struvite
2.	Silicon Dioxide (Silica)
3.	Dentifrices (Dentifrice)
4.	fluorophosphate (sodium monofluorophosphate)
5.	Sodium Fluoride (Ossin)
6.	Cystine (L-Cystine)
7.	Calcium Oxalate
8.	Uric Acid (Urate)
9.	calcium phosphate
10.	tetracalcium phosphate

Related Therapies and Procedures

1.	Lithotripsy (Extracorporeal Shockwave Lithotripsy)
2.	Gas Lasers
3.	Dye Lasers
4.	Lower Body Negative Pressure
5.	Injections